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FLONASE® Glaxo Wellcome Fluticasone Propionate Corticosteroid for Nasal Use Action And Clinical Pharmacology: Fluticasone is a potent anti-inflammatory steroid with strong topical and weak systemic activity. When administered intranasally in therapeutic doses, it has a direct anti-inflammatory action on the nasal mucosa, the mechanism of which is not yet completely defined. The onset of action is not immediate, and 2 to 3 days treatment may be required before maximum relief…

FLOMAX® Boehringer Ingelheim Tamsulosin HCl Selective Antagonist of Alpha1A-adrenoceptor Subtype in the Prostate Action And Clinical Pharmacology: Tamsulosin, an alpha1-adrenoceptor blocking agent, exhibits selectivity for alpha1 receptors in the human prostate. At least 3 discrete alpha1-adrenoreceptor subtypes have been identified: alpha1A, alpha1B and alpha1D; their distribution differs between human organs and tissue. Approximately 70% of the alpha1-receptor in human prostate is of the alpha1A subtype. The symptoms associated with benign…

FLEXALL® STICK Chattem Menthol – Methyl Salicylate Topical Analgesic Indications And Clinical Uses: For temporary relief from minor arthritis pain, bursitis, tendonitis, backache, strains and sprains. Manufacturers’ Warnings In Clinical States: For external use only. Keep out of the reach of children. Keep away from eyes, mucous membranes, broken or irritated skin. If rash or excessive irritation occurs, discontinue use. If condition worsens or persists for more than 7 days,…

FLAMAZINE® C Smith & Nephew Silver Sulfadiazine – Chlorhexidine Digluconate Topical Antibacterial Action And Clinical Pharmacology: The mechanism of silver sulfadiazine’s antibacterial action has not been fully elucidated. After exposure to the drug, structural changes in the bacterial cell membrane occur, including distortion and enlargement of the cell and a weakening of the cell wall membrane. This is accompanied by reduced viability in sensitive strains. The silver sulfadiazine molecule dissociates…

FLAREX® Alcon Fluorometholone Acetate Corticosteroid Action And Clinical Pharmacology: Adrenocorticoids suppress the inflammatory response (edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, deposition of collagen and scar formation) to chemical, immunological or mechanical irritants. Adrenocorticoids may cause a rise in intraocular pressure in susceptible individuals. They are absorbed into aqueous humor, cornea, iris, choroid, ciliary body, and retina. Systemic absorption occurs but may be significant only at higher doses…

FIORINAL® Novartis Pharmaceuticals ASA – Caffeine – Butalbital Analgesic – Sedative Indications And Clinical Uses: For tension (or muscle contraction) headache and conditions where a simultaneous sedative and analgesic action is required, such as mixed migraine headaches, menstrual and postpartum tension and pain. Contraindications, Precautions and Adverse Effects: See Fiorinal-C monograph. A possible association between Reye’s syndrome and the use of salicylates has been suggested but not established. Reye’s syndrome…

FIORINAL®-C 1/4, 1/2 Novartis Pharmaceuticals ASA – Caffeine – Codeine – Butalbital Analgesic – Sedative Indications And Clinical Uses: The relief of acute and chronic pain of mild, moderate, or severe degree, which is accompanied by tension or anxiety and in all indications where a simultaneous sedative and analgesic action is required, such as: tension headache, musculoskeletal pain, including low back pain, postoperative, post partum pain, dysmenorrhea, pain associated with…

FERMALAC® VAGINAL Rougier Lactobacillus Acidophilus Compound Vaginitis Therapy Indications And Clinical Uses: Adjunctive treatment of specific vaginal infections to restore and maintain normal vaginal flora. Dosage: One capsule inserted into the vagina once daily at bedtime for 10 consecutive days or as prescribed. Availability And Storage: Each opaque white No. 000 capsule contains: more than 2 billion fully viable bacilli (lyophilized cultures) – Lactobacillus acidophilus, Lactobacillus bulgaricus and Streptococcus lactis…

FERTINORM® HP Serono Urofollitropin Gonadotropin Action And Clinical Pharmacology: Fertinorm HP is a highly purified preparation of the gonadotropin, Follicle Stimulating Hormone (FSH) extracted from the urine of postmenopausal women. The principal action of Fertinorm HP is the induction of follicular growth in infertile women who do not have primary ovarian failure. Treatment in most instances results only in follicular growth and maturation. In order to effect ovulation in the…

FEXICAM Technilab Piroxicam Nonsteroidal Anti-inflammatory – Analgesic – Antipyretic Action And Clinical Pharmacology: Piroxicam is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. Its mechanism of action is incompletely known. Piroxicam inhibits the activity of prostaglandin synthetase. Its anti-inflammatory action may be partially explained by the resulting decrease in prostaglandin biosynthesis. Its therapeutic action is not due to pituitary-adrenal stimulation. In rheumatoid arthritis the efficacy of piroxicam 20 mg…