ROYCHLOR® Waymar Potassium Chloride Potassium Replacement Therapy Indications And Clinical Uses: The treatment of potassium depletion found in patients with hypokalemia and metabolic alkalosis, digitalis intoxication, inadequate dietary potassium intake and those patients receiving digitalis and diuretics, e.g. congestive heart failure, and hepatic cirrhosis with ascites. For treatment of hypertensive patients undergoing longterm diuretic therapy, hyperaldosteronism states with normal renal function, potassium losing nephropathy and certain diarrheal states. Contra-Indications: In…
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Roychlor (Potassium Chloride)
(Pharmaceutical)Royvac (Magnesium Citrate – Bisacodyl)
(Pharmaceutical)ROYVAC® Waymar Magnesium Citrate – Bisacodyl Bowel Evacuant Indications And Clinical Uses: Preparation of the colon for radiology (prior to barium enemas or i.v. pyelograms) surgery and many proctological procedures. Precautions: Do not use any of these preparations when undiagnosed abdominal pain, nausea or vomiting are present. Frequent or prolonged use of these preparations may result in dependence on laxatives. Do not administer Royvac to persons who cannot swallow without…
Rubramin
(Pharmaceutical)RUBRAMIN® Squibb Vitamin B12 Hematopoietic Action And Clinical Pharmacology: Vitamin B is essential for growth, cell reproduction, hematopoiesis, nucleoprotein and myelin synthesis. Within 48 hours after injection of 100 to 1 000 µg of vitamin B12, 50 to 98% of the injected dose may appear in the urine. The major portion is excreted within the first 8 hours. Indications And Clinical Uses: For vitamin B12 deficiency occurring in: pernicious anemia…
Rythmodan (Disopyramide)
(Pharmaceutical)RYTHMODAN® RYTHMODAN®-LA Hoechst Marion Roussel Disopyramide Antiarrhythmic Agent Action And Clinical Pharmacology: In both animal and man the electrophysiological and hemodynamic effects of disopyramide are qualitatively similar to those of quinidine and procainamide. Although the exact mechanism of action has not been completely elucidated, it would appear from animal studies that disopyramide exerts its antiarrhythmic activity in the following manner: 1. Reduces automaticity in cardiac Purkinje fibers by depressing the…
Roferon (Interferon alfa-2a)
(Pharmaceutical)ROFERON®-A Roche Interferon alfa-2a Biological Response Modifier Action And Clinical Pharmacology: The mechanisms by which interferon alfa-2a, or any other interferon, exerts antitumor activity are not clearly understood. However, it is believed that the direct antiproliferative action against tumor cells and modulation of the host immune response play important roles in the antitumor activity. Interferon alfa-2a has been shown to exert antiproliferative activity against a variety of human tumors in…
Rovamycine (Spiramycin)
(Pharmaceutical)ROVAMYCINE® Rhône-Poulenc Rorer Spiramycin Antibiotic Action And Clinical Pharmacology: It is active against the following gram-positive organisms: S. aureus (including penicillin resistant strains), beta-hemolytic streptococci, S. viridans, S. faecalis and S. pneumoniae, C. diphtheriae, clostridia. Except for B. pertussis, H. influenzae (approximately 50% of strains) and neisseria, gram-negative organisms are generally considered as resistant to spiramycin. Bacterial resistance to spiramycin has been reported to develop, including cross resistance between spiramycin…
Robinul (Glycopyrrolate)
(Pharmaceutical)ROBINUL® ROBINUL® FORTE Wyeth-Ayerst Glycopyrrolate Anticholinergic Indications And Clinical Uses: The management of gastrointestinal disorders amenable to anticholinergic therapy, such as: duodenal ulcer, duodenitis, pylorospasm; gastric ulcer, gastritis, hiatal hernia, hyperchlorhydria, pyrosis, aerophagia, gastroenteritis; esophagitis; cholecystitis, chronic pancreatitis; spastic and irritable colon, ulcerative colitis, functional bowel distress, diverticulitis, acute enteritis, diarrhea; and splenic flexure syndrome, neurogenic gastrointestinal disturbances. Contra-Indications: Glaucoma, urinary bladder neck obstruction, pyloric obstruction, stenosis with significant gastric…
Robitussin (Guaifenesin)
(Pharmaceutical)Introduction Robitussin (guaifenesin) is an expectorant. It helps reduce congestion in your chest and throat, making it easier for you to cough out through your mouth. Here’s everything you need to know, including how it works, as well as uses, contraindications, side effects, interactions, storage and precautions. Action And Clinical Pharmacology Guaifenesin enhances the output of lower respiratory tract fluid. The enhanced flow of less viscid secretions promotes ciliary action, and…
Rocaltrol (Calcitriol)
(Pharmaceutical)ROCALTROL® Roche Calcitriol Vitamin D3 Metabolite Action And Clinical Pharmacology: The supply of vitamin D in man depends on dietary intake and/or exposure to the ultraviolet rays of the sun for conversion of 7-dehydrocholesterol to vitamin D3 (cholecalciferol). Vitamin D3 (cholecalciferol) must be metabolized in the liver and the kidneys before it is fully active on its target tissues. The initial transformation is catalyzed by a vitamin D3-25-hydroxylase enzyme (25-OH-ase)…
Robinul (Glycopyrrolate)
(Pharmaceutical)ROBINUL® INJECTABLE Wyeth-Ayerst Glycopyrrolate Anticholinergic Action And Clinical Pharmacology: Glycopyrrolate, like other anticholinergic (antimuscarinic) agents, competitively antagonizes the action of acetylcholine on structures innervated by postganglionic cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation. Glycopyrrolate antagonizes muscarinic symptoms (e.g., bronchorrhea, bronchospasm, bradycardia and intestinal hypermotility) induced by cholinergic drugs such as the anticholinesterases. As a premedicant, glycopyrrolate injectable reduces excessive pharyngeal, tracheal and bronchial…