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SOLGANAL Schering Aurothioglucose Antirheumatic Agent Action and Clinical Although the mechanism of action is not well understood, gold compounds have been reported to decrease synovial inflammation and retard cartilage and bone destruction.: Gold is absorbed from injection sites, reaching peak concentration in blood in 4 to 6 hours. Following a single i.m. injection of 50 mg aurothioglucose suspension in each of 2 patients, peak serum levels were about 235 g/dL…

SOFRA-TULLE® Hoechst Marion Roussel Framycetin Sulfate Topical Antibiotic Action and Clinical Framycetin, a broad spectrum aminoglycoside antibiotic, is usually bactericidal in action. Although the exact mechanism of action has not been fully elucidated, the drug appears to inhibit protein synthesis in susceptible bacteria by binding to ribosomal subunits. In general, framycetin is active against many aerobic gram-negative bacteria and some aerobic gram-positive bacteria, namely staphylococci including S. aureus. The drug is…

SODIUM CHLORIDE INJECTION, USP Abbott Isotonic Vehicle-Electrolyte Replenisher Availability And Storage: Bacteriostatic with Preservative: Each mL contains: sodium chloride 9 mg. Also contains benzyl alcohol and hydrochloric acid. Fliptop plastic vials of 10, 20, 30 and 100 mL. Boxes of 10 and 25. Preservative-free: Each mL contains: sodium chloride 9 mg. Also contains hydrochloric acid and/or sodium hydroxide. Osmolarity: 0.3 m0smol/mL. Fliptop plastic vials of 10 and 20 mL. Boxes…

SODIUM CHLORIDE IRRIGATION SOLUTION USP AstraZeneca Sodium Chloride Irrigation Solution Indications And Clinical Uses: A sterile solution which exerts a mechanical cleansing action for: sterile irrigation of body cavities, tissues, wounds, indwelling urethral catheters, surgical drainage tubes; washing and rinsing purposes that allow use of a sterile nonpyrogenic electrolyte solution; soaking of surgical dressings, instruments and laboratory specimens. Contra-Indications: Sodium chloride irrigation solution 0.9% is for topical use only and should never…

SODIUM SULAMYD® Schering Sulfacetamide Sodium Ophthalmic Antibacterial Indications And Clinical Uses: The treatment of conjunctivitis, corneal ulcer, and other superficial ocular infections due to susceptible microorganisms, and as adjunctive treatment in systemic therapy of trachoma. Contra-Indications: Hypersensitivity to sulfonamide preparations. Precautions: The solutions are incompatible with silver preparations. Ophthalmic ointments may retard corneal healing. Nonsusceptible organisms, including fungi, may proliferate with the use of these preparations. Do not use solutions…

EDECRIN®, SODIUM EDECRIN® Merck Frosst Ethacrynic Acid, Ethacrynate Sodium Diuretic-Salureticö Action and Clinical Pharmacology: Ethacrynic acid is a saluretic-diuretic agent with marked potency and rapid onset of action. It is chemically unrelated to other diuretics. Patients with congestive heart failure (including acute pulmonary edema), renal edema, hepatic cirrhosis with ascites, and other conditions involving fluid retention have responded well to ethacrynic acid. Ethacrynic acid has the following major characteristics: Water…

Serostim for Injection (Serono) DESCRIPTION Serostim® [somatropin (rDNA origin) for injection] is a human growth hormone produced by recombinant DNA technology. Serostim® has 191 amino acid residues and a molecular weight of 22,125 daltons. Its amino acid sequence and structure are identical to the dominant form of human pituitary growth hormone. Serostim® is produced by a mammalian cell line (mouse C127) that has been modified by the addition of the…

Serzone Bristol-Myers Squibb DESCRIPTION SERZONE® (nefazodone hydrochloride) is an antidepressant for oral administration with a chemical structure unrelated to selective serotonin reuptake inhibitors, tricyclics, tetracyclics, or monoamine oxidase inhibitors (MAOI). Nefazodone hydrochloride is a synthetically derived phenylpiperazine antidepressant. The chemical name for nefazodone hydrochloride is 2-[3-[4-(3-chlorophenyl)-1-piperazinyl] propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one monohydrochloride. The molecular formula is C 25 H 32 ClN 5 O 2 HCl, which corresponds to a molecular weight of 506.5. Nefazodone…

SODIUM CHLORIDE INJECTION USP AstraZeneca Isotonic Saline Indications And Clinical Uses: Sodium chloride injection USP can be used as an isotonic vehicle for many parenteral drugs. Injections may also be administered s.c. to infants in conjunction with hyaluronidase, which facilitates the absorption of the fluid. Precautions: Cardiovascular disease; patients receiving corticosteroids, corticotropin or drugs that may give rise to sodium retention. Adverse Reactions: Excessive amounts by any route may cause…

Seromycin Capsules (Dura) DESCRIPTION Seromycin® (Cycloserine Capsules, USP), 3-isoxazolidinone, 4-amino-, (R)- is a broad-spectrum antibiotic that is produced by a strain of Streptomyces orchidaceus and has also been synthesized. Cycloserine is a white to off-white powder that is soluble in water and stable in alkaline solution. It is rapidly destroyed at a neutral or acid pH. Cycloserine has a pH between 5.5 and 6.5 in a solution containing 100 mg/mL….