Sodium Chloride Injection USP

Medically reviewed by Melisa Puckey. Last updated on March 29, 2024

SODIUM CHLORIDE INJECTION USP

AstraZeneca

Isotonic Saline

Indications And Clinical Uses:

Sodium chloride injection USP can be used as an isotonic vehicle for many parenteral drugs. Injections may also be administered s.c. to infants in conjunction with hyaluronidase, which facilitates the absorption of the fluid.

Precautions:

Cardiovascular disease; patients receiving corticosteroids, corticotropin or drugs that may give rise to sodium retention.

Adverse Reactions:

Excessive amounts by any route may cause hypokalemia and acidosis.

Excessive amounts by the parenteral route may precipitate congestive heart failure and acute pulmonary edema, especially in patients with cardiovascular disease.

Dosage And Administration:

Parenterally, 0.45 to 0.9% solution, amount and concentration varying with circumstances.

Availability & Storage:

Each mL contains: sodium chloride 9 mg in single use glass vials or plastic ampuls (Polyamp Duofit) (suitable for Luer fit and Luer lock syringes) of 10 mL. Preservative-free. The solution has an osmolarity of approximately 0.31 mOsm/mL (calc.). Do not use if solution is cloudy or contains a precipitate. Discard unused portion. Store at room temperature (15 to 30°C).

SODIUM CHLORIDE INJECTION USP AstraZeneca Isotonic Saline

About Melisa Puckey

Melisa Puckey, BPharm is a New Zealand–registered pharmacist accredited to supply emergency contraception, sildenafil, trimethoprim, chloramphenicol, and clozapine. She has over ten years of experience in community pharmacy, focusing on patient care, medication safety, and treatment accuracy. Her medical writing centers on evidence-based topics including COVID-19, oncology, dermatology, and reproductive health. Melisa is a member of the Pharmaceutical Society of New Zealand, the Australasian Medical Writers' Association, and the American Medical Writers Association.