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ELAVIL® MSD Amitriptyline HCl Antidepressant Indications And Clinical Uses: In the drug management of depressive illness. Amitriptyline may be used in depressive illness of psychotic or endogenous nature and in selected patients with neurotic depression. Endogenous depression is more likely to be alleviated than are other depressive states. Amitriptyline, because of its sedative action, is also of value in alleviating the anxiety component of depression. As with other tricyclic antidepressants,…

ELDEPRYL® Draxis Health Selegiline HCl Antiparkinsonian Agent Action And Clinical Pharmacology: Selegiline is an irreversible inhibitor of the enzyme monoamine oxidase (MAO). Because selegiline has greater affinity for type B than type A MAO, it can serve as a selective inhibitor of MAO-B if it is administered at the recommended dose. Selegiline may have pharmacological effects unrelated to MAO-B inhibition. There is some evidence that it may increase dopaminergic activity…

EDECRIN® SODIUM EDECRIN® MSD Ethacrynic Acid Ethacrynate Sodium Diuretic – Saluretic Action And Clinical Pharmacology: Ethacrynic acid is a saluretic-diuretic agent with marked potency and rapid onset of action. It is chemically unrelated to other diuretics. Patients with congestive heart failure (including acute pulmonary edema), renal edema, hepatic cirrhosis with ascites, and other conditions involving fluid retention have responded well to ethacrynic acid. Ethacrynic acid has the following major characteristics:…

DRISTAN® N.D. DRISTAN® N.D. EXTRA STRENGTH Whitehall-Robins Acetaminophen – Pseudoephedrine HCl Analgesic – Decongestant Indications And Clinical Uses: For the symptomatic relief of colds, sinusitis, nasal congestion, sneezing, runny nose, fever, headache, minor aches and pains. Contra-Indications: Hypersensitivity to any of the components. Patients receiving MAO inhibitors. Precautions: Use with caution on elderly patients or those with hypertension, diabetes, glaucoma, coronary artery disease, hyperthyroidism, prostatic hypertrophy and patients receiving MAO…

ECHOVIST® Berlex Canada Galactose Ultrasound Contrast Agent Action And Clinical Pharmacology: Echovist is an ultrasound contrast agent consisting of a suspension of micron-sized air bubbles, formed upon reconstitution of specially formulated galactose granules with an aqueous galactose solution. Following intrauterine administration of the suspension, the bubbles serve to enhance ultrasound signals from the uterine cavity and fallopian tubes, thus enabling better visualization of these structures. Upon completion of the ultrasound…

ECOSTATIN® Preparations Westwood-Squibb Econazole Nitrate Antifungal Agent Action And Clinical Pharmacology: Econazole exhibits antifungal activity against a wide variety of fungi, including dermatophytes, pathogenic yeasts, and moulds. Susceptible pathogenic organisms include C. albicans and other Candida species, T. rubrum, T. mentagrophytes, E. floccosum and M. furfur. It appears to act by altering the internal structure or cell membrane permeability of the fungus. tag_IndicationsIndications Indications And Clinical Uses: Cream: The treatment…

DRISTAN® DRISTAN® EXTRA STRENGTH Whitehall-Robins Phenylephrine – Chlorpheniramine – Acetaminophen Decongestant – Antihistamine – Analgesic Indications And Clinical Uses: For the symptomatic relief of colds, sinusitis, hay fever or other upper respiratory allergies, nasal congestion, sneezing, runny nose, fever, headache, minor aches and pains. Contra-Indications: Hypersensitivity to any of the components. Patients receiving MAO inhibitors. Precautions: Use with caution on elderly patients or patients with allergy to acetaminophen, chronic alcoholism,…

DPE™ Alcon Dipivefrin HCl Glaucoma Therapy Action And Clinical Pharmacology: Dipivefrin is converted to epinephrine inside the human eye by enzyme hydrolysis. The liberated epinephrine, an adrenergic agonist, appears to exert its action by decreasing aqueous production and by enhancing outflow facility. The dipivefrin hydrochloride prodrug delivery system is a more efficient way of delivering the therapeutic effects of epinephrine, with fewer side effects than are associated with conventional epinephrine…

DRISTAN® NASAL MIST/SPRAY Whitehall-Robins Pheniramine – Phenylephrine Nasal Decongestant Action And Clinical Pharmacology: Phenylephrine is a sympathomimetic agent that constricts the smaller arterioles of the nasal passages producing a gentle and predictable decongesting effect. Pheniramine is an antihistamine that controls rhinorrhea, sneezing and lacrimation associated with elevated histamine levels in disorders of the respiratory tract. Indications And Clinical Uses: Prompt temporary relief of nasal congestion due to colds, sinusitis, hay…

DOLOBID® Frosst Diflunisal Analgesic – Anti-inflammatory Action And Clinical Pharmacology: Diflunisal is a nonsteroidal drug with analgesic, anti-inflammatory and antipyretic properties. The precise mechanism of the analgesic and anti-inflammatory actions of diflunisal is not known; however, it appears to be a peripherally acting analgesic drug. Diflunisal is a prostaglandin synthetase inhibitor. In animals, prostaglandin sensitize afferent nerves and potentiate the action of bradykinin in inducing pain. Since prostaglandins are known…