You searched for : 'U'

ACTINAC® Hoechst Marion Roussel Chloramphenicol – Hydrocortisone Acetate – Butoxyethylnicotinate – Allantoin – Precipitated Sulfur Acne Therapy Action And Clinical Pharmacology: The roles of the individual ingredients in Actinac and their collective mechanisms of action in the topical treatment of acne have not been elucidated. Hydrocortisone, chloramphenicol and precipitated sulfur are however, widely recognized for their respective anti-inflammatory, antibacterial and desquamating properties. Chloramphenicol is usually bacteriostatic in action, but may…

ACTIVASE® rt-PA Roche Alteplase Fibrinolytic Agent Action And Clinical Pharmacology: Alteplase is a serine protease which has the property of fibrin-enhanced conversion of plasminogen to plasmin. It produces minimal conversion of plasminogen in the absence of fibrin; and when introduced into the systemic circulation, alteplase binds to fibrin in a thrombus and converts the entrapped plasminogen to plasmin. This initiates local fibrinolysis with minimal systemic effects. Following administration of alteplase…

ACEL-P™ Wyeth-Ayerst Acellular Pertussis Vaccine Adsorbed Active Immunizing Agent Action And Clinical Pharmacology: Pertussis disease (whooping cough) is caused by a gram-negative coccobacillus, B. pertussis. Acellular pertussis vaccine adsorbed is an acellular pertussis vaccine indicated for primary immunization against disease caused by B. pertussis. Pertussis (whooping cough) has 3 typical stages (catarrhal, paroxysmal, and convalescent). The second phase is characterized by severe paroxysmal coughing that persists for weeks. The disease…

ACNOMEL® Acne Mask Chattem Salicylic Acid Acne Therapy Indications And Clinical Uses: For treatment of acne. Precautions: Avoid contact with eyes. Dosage: Splash face with warm water. Apply the acne mask over entire face, avoiding eyes. Leave on as a mask for 10 minutes. Rinse off with warm water. Use once or twice weekly. Availability And Storage: Each mL contains: salicylic acid 1.5% in cream base with 100% natural clays….

Act-HIB® Connaught Haemophilus b Conjugate Vaccine (Tetanus Protein – Conjugate) Active Immunizing Agent Action And Clinical Pharmacology: Clinical Data (PRP-T): Haemophilus b Conjugate Vaccine has been administered during clinical trials to over 110 000 infants and children in Canada, the U.S., Finland, France, Chile, Israel, and the United Kingdom using local immunization schedules, and has been used widely in immunization programmes. In clinical trials where 921 infants were given the…

ACE INHIBITORS General Monograph, Benazepril Captopril Cilazapril Enalapril Enalaprilat Fosinopril Lisinopril Perindopril Quinapril Ramipril Trandolapril Angiotensin Converting Enzyme Inhibitor, Action And Clinical Pharmacology: The renin-angiotensin system is a complex neuroendocrine system involved in the regulation of hemodynamics and water and electrolyte balance. When released from the kidney in response to a decrease in blood volume, renal perfusion pressure or plasma sodium concentration, renin acts on its substrate, angiotensinogen, to form…

ABENOL® SmithKline Beecham Acetaminophen Analgesic – Antipyretic Action And Clinical Pharmacology: Acetaminophen is the major metabolite of phenacetin and acetanilide. Animal and clinical studies have shown acetaminophen to have antipyretic and analgesic activity equal to that of ASA. Acetaminophen lacks anti-inflammatory effects. Unlike the salicylates, acetaminophen does not interfere with tubular secretion of uric acid nor does it affect acid-base balance if taken in therapeutic doses. Acetaminophen does not interfere…

AXID® Lilly Nizatidine Histamine H2 Receptor Antagonist Action And Clinical Pharmacology: Nizatidine is a competitive, reversible inhibitor of the histamine H2 receptor of gastric-acid secreting cells. Nizatidine is not an anticholinergic agent. It inhibits nocturnal gastric-acid secretion and gastric-acid secretion stimulated by food, caffeine, betazole and pentagastrin. Pepsin output is reduced in proportion to the reduced volume of gastric secretions. Nizatidine has little or no effect on basal serum gastrin…

AZMACORT® Rhône-Poulenc Rorer Triamcinolone Acetonide Corticosteroid Action And Clinical Pharmacology: Triamcinolone is a potent anti-inflammatory steroid with strong topical and weak systemic activity. When inhaled at therapeutic dosages, it has a direct anti-inflammatory action on the bronchial mucosa. Since the minute amounts absorbed do not exert any significant systemic effect, inhaled triamcinolone can replace oral steroids with the elimination of the untoward effects of systemic therapy. Indications And Clinical Uses:…

AVIRAX™ Fabrigen Acyclovir Antiviral Action And Clinical Pharmacology: Acyclovir, a synthetic acyclic nucleoside analog, is a substrate with a high degree of specificity for herpes simplex and varicella-zoster specified thymidine kinase. Acyclovir is a poor substrate for host cell-specified thymidine kinase. Herpes simplex and varicella-zoster specified thymidine kinase transform acyclovir to its monophosphate which is then transformed by a number of cellular enzymes to acyclovir diphosphate and acyclovir triphosphate. Acyclovir…