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BACTIGRAS® Smith & Nephew Chlorhexidine Acetate Topical Antibacterial Action And Clinical Pharmacology: Chlorhexidine inhibits the growth of vegetative gram-positive and gram-negative organisms in vitro. Acid fast bacilli and heat resistant bacterial spores are not susceptible to the lethal action of chlorhexidine even in strong concentrations at room temperature. Chlorhexidine has greater activity in alkaline media. Adsorption of chlorhexidine on organic matter, pus, serum, blood, etc. will cause a reduction in…

BACITRACIN Pharmacia & Upjohn Antibiotic Action And Clinical Pharmacology: Bacitracin, an antibiotic substance derived from cultures of B. subtilis (Tracey), exerts pronounced antibacterial action in vitro against a variety of gram-positive and a few gram-negative organisms. However, among systemic diseases, only staphylococcal infections qualify for consideration of bacitracin therapy. Bacitracin is assayed against a standard and its activity is expressed in units, 1 mg having a potency of not less…

BABY’S OWN™ OINTMENT Block Drug Zinc Oxide Skin Protective Indications And Clinical Uses: Prevention and relief of diaper rash. Warnings: For external use only. Avoid contact with eyes. If eye contact occurs, rinse thoroughly with water. Discontinue use if rash occurs or worsens. Keep out of the reach of children. Dosage: To relieve diaper rash apply 3 or more times daily at first sign of redness. To prevent diaper rash…

BABY’S OWN™ INFANT DROPS Block Drug Simethicone Antiflatulent Indications And Clinical Uses: To relieve infant colic, bloating and flatulence due to gas. Warnings: Keep this and all drugs out of the reach of children. Do not take for more than 2 weeks unless directed by a physician. If symptoms recur consult a physician. Dosage: Shake well before using. Use only on the advice of a physician. Infants (under 2 years):…

BABY’S OWN™ TEETHING GEL Block Drug Benzyl Alcohol Topical Analgesic Indications And Clinical Uses: For quick relief from teething pain by its topical anesthetic effect on sore gums. Warnings: Keep this and all medications out of the reach of children. Dosage: Wash hands. Apply small amount directly to sore gums. Repeat, if necessary, every 4 hours. If symptoms persist, consult physician. Availability And Storage: Each pleasantly flavored g of gel…

ASASANTINE® Boehringer Ingelheim Dipyridamole – ASA Inhibitor of Platelet Adhesion and Aggregation Action And Clinical Pharmacology: The combined use of dipyridamole and ASA causes a significant reduction in the incidence of new fatal and nonfatal coronary events in patients with a previously documented myocardial infarction. In a randomized, double blind study, the effects of combined dipyridamole and ASA treatment were compared to ASA alone and to placebo in 2 026…

ARISTOSPAN® Stiefel/Glades Triamcinolone Hexacetonide Glucocorticoid Action And Clinical Pharmacology: The hexacetonide ester of triamcinolone is relatively insoluble (0.0002% at 25°C in water). When injected intra-articularly it can be expected to be absorbed slowly from the injection site. The pharmacological action of triamcinolone hexacetonide is less intense and more prolonged, but qualitatively the same as triamcinolone acetonide. Triamcinolone hexacetonide’s activity is ascribable to the slow release of triamcinolone acetonide through hydrolysis….

ARLIDIN® ARLIDIN® FORTE Rhône-Poulenc Rorer Nylidrin HCl Peripheral Vasodilator – Organic Brain Syndrome Therapy Action And Clinical Pharmacology: Nylidrin acts predominantly by beta receptor stimulation. It has been shown to dilate arterioles in skeletal muscle and to increase cardiac output. An increase in cerebral blood flow and a decrease in vascular resistance has also been reported. The result of this combination of actions is a greater blood supply to ischemic…

ASACOL® Procter & Gamble Pharmaceuticals 5-ASA Lower Gastrointestinal Anti-inflammatory Action And Clinical Pharmacology: The active ingredient in Asacol, mesalamine (5-aminosalicylic acid, also referred to as 5-ASA), is the major active component of sulfasalazine for the treatment of inflammatory bowel disease. The available evidence suggests that mesalamine has a topical anti-inflammatory effect on the colon, where it inhibits prostaglandin and leukotriene synthesis. Asacol tablets have a special acrylic-based resin coating which…

ARISTOCORT® Parenteral Stiefel/Glades Triamcinolone Diacetate Corticosteroid Indications And Clinical Uses: Intralesional Injection: For intralesional or sublesional use in local therapy of various skin diseases, e.g. psoriasis, alopecia areata, neurodermatitis, atopic dermatitis, acne, synovial and sebaceous cysts, pruritus ani, contact and nummular dermatoses. Not for i.v. use. Forte Parenteral: For i.m., intrasynovial or intra-articular injection. Not for i.v. use. May be used in the treatment of asthma, allergies, ulcerative colitis, collagen…