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FLEXERIL® Frosst Cyclobenzaprine HCl Skeletal Muscle Relaxant Action And Clinical Pharmacology: Cyclobenzaprine relieves skeletal muscle spasm of local origin without interfering with muscle function. It is ineffective in muscle spasm due to CNS disease. Controlled clinical studies show that cyclobenzaprine improves the signs and the symptoms of skeletal muscle spasm. Pharmacokinetics: Cyclobenzaprine is well absorbed in man. After oral or i.v. doses (10 mg) of 4-labeled cyclobenzaprine to human subjects,…

FLEXALL® Chattem Menthol Topical Analgesic Indications And Clinical Uses: For temporary relief from minor arthritis pain, bursitis, tendonitis, backache, strains and sprains. Warnings: For external use only. Keep out of the reach of children. Keep away from eyes, mucous membranes, broken or irritated skin. If rash occurs, discontinue use. Do not bandage tightly or use heating pad. Dosage: Apply generously to muscles and joints and gently massage until gel disappears….

FLEXALL® STICK Chattem Menthol – Methyl Salicylate Topical Analgesic Indications And Clinical Uses: For temporary relief from minor arthritis pain, bursitis, tendonitis, backache, strains and sprains. Manufacturers’ Warnings In Clinical States: For external use only. Keep out of the reach of children. Keep away from eyes, mucous membranes, broken or irritated skin. If rash or excessive irritation occurs, discontinue use. If condition worsens or persists for more than 7 days,…

FLAXEDIL® Rh´ne-Poulenc Rorer Gallamine Triethiodide Muscle Relaxant Action And Clinical Pharmacology: Gallamine is a competitive neuromuscular blocking agent. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. Gallamine has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release. Following usual i.v. doses muscle relaxation occurs rapidly and reaches a…

FLAGYL® Rh´ne-Poulenc Rorer Metronidazole Antibacterial – Antiprotozoal Action And Clinical Pharmacology: Metronidazole is bactericidal against anaerobic bacteria, it exerts trichomonacidal activity and is also active against Giardia lamblia and Entamoeba histolytica. Its exact mechanism of action has not been entirely determined as yet. It has been proposed that an intermediate in the reduction of metronidazole, produced only in anaerobic bacteria and protozoa is bound to deoxyribonucleic acid and electron-transport proteins,…

FLAGYSTATIN® R´ne-Poulenc Rorer Metronidazole – Nystatin Trichomonacide – Moniliacide Indications And Clinical Uses: Mixed vaginal infection due to Trichomonas vaginalis and C. albicans. Contra-Indications: Hypersensitivity to either of the components. Combined treatment with oral Flagyl should be avoided in cases of active neurological disorders or a history of blood dyscrasia, hypothyroidism or hypoadrenalism unless in the opinion of the physician the benefits outweigh the possible hazard to the patient. See…

FERMENTOL® Carter Horner Pepsin Digestant Indications And Clinical Uses: For the relief of mild, acute and chronic dyspepsia without hyperacidity, and as a vehicle for the administration of medicinals compatible with alcohol. Dosage: 5 mL after meals for chronic indigestion; 30 mL for acute indigestion. As a vehicle, the mixture should contain at least 50% Fermentol, 80% is recommended. Availability And Storage: Each 30 mL of green-colored, transparent liquid contains:…

FEXICAM Technilab Piroxicam Nonsteroidal Anti-inflammatory – Analgesic – Antipyretic Action And Clinical Pharmacology: Piroxicam is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. Its mechanism of action is incompletely known. Piroxicam inhibits the activity of prostaglandin synthetase. Its anti-inflammatory action may be partially explained by the resulting decrease in prostaglandin biosynthesis. Its therapeutic action is not due to pituitary-adrenal stimulation. In rheumatoid arthritis the efficacy of piroxicam 20 mg…

FEMARA® Novartis Pharmaceuticals Letrozole Nonsteroidal Aromatase Inhibitor – Inhibitor of Estrogen Biosynthesis – Antitumor Agent Action And Clinical Pharmacology: Letrozole is a potent and highly specific nonsteroidal aromatase inhibitor. It inhibits the aromatase enzyme by competitively binding to the heme of the cytochrome P450 subunit of the enzyme, resulting in a reduction of estrogen biosynthesis in all tissues. Letrozole exerts its antitumor effect by depriving estrogen-dependent breast cancer cells of…

FELDENE™ Pfizer Piroxicam Anti-inflammatory – Analgesic Action And Clinical Pharmacology: Piroxicam is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. Its mechanism of action is incompletely known. Piroxicam inhibits the activity of prostaglandin synthetase. The resulting decrease in prostaglandin biosynthesis may partially explain its anti-inflammatory action. Piroxicam does not act by pituitary-adrenal stimulation. In rheumatoid arthritis the efficacy of piroxicam 20 mg daily has been found to be similar…