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BECONASE Aq® Glaxo Wellcome Beclomethasone Dipropionate Corticosteroid for Nasal Use Action And Clinical Pharmacology: Beclomethasone dipropionate is a potent anti-inflammatory steroid with strong topical and weak systemic activity. When inhaled intranasally at therapeutic doses, it has a direct anti-inflammatory action within the nasal mucosa, the mechanism of which is not yet completely defined. The minute amount absorbed in therapeutic doses has not been shown to exert any apparent clinical systemic…

AQUATAIN® Whitehall-Robins Emollient Indications And Clinical Uses: Emollient for dry, chapped, rough skin. Dosage: Apply as needed several times daily or as prescribed. Availability And Storage: Cream: Each tube of unscented, hypoallergenic cream contains: benzyl alcohol, polawax, isopropyl palmitate, glycerin, sorbitol, lactic acid and water. Tartrazine-free. Tubes of 75 g. Lotion: Each bottle of unscented, hypoallergenic lotion contains: benzyl alcohol, polawax, isopropyl palmitate, glycerin, sorbitol, lactic acid and water. Tartrazine-free….

AQUASOL® E Novartis Consumer Health Vitamin E Vitamin Action And Clinical Pharmacology: Vitamin E is a fat soluble vitamin which is present in many foods and exists in a variety of forms. It is considered an essential element of human nutrition, with many of its actions related to its antioxidant properties. Indications And Clinical Uses: A nutritional supplement for the treatment of vitamin E deficiency. Vitamin E deficiency states are…

ARALEN® Sanofi Chloroquine Phosphate Antimalarial – Antiparasitic Action And Clinical Pharmacology: Chloroquine has been found to be highly active against the erythrocytic forms of Plasmodium vivax, ovale and malariae and many strains of Plasmodium falciparum (but not the gametocytes of Plasmodium falciparum). The precise mechanism of plasmodicidal action of the drug is not known. While the drug can inhibit certain enzymes, its effect is believed to result, in part, from…

AQUACORT® Spectropharm Dermatology Hydrocortisone Topical Corticosteroid Action And Clinical Pharmacology: Topical corticosteroids are synthetic derivatives of cortisone which are effective when applied locally to control many types of inflammatory, allergic and pruritic dermatoses. They are thought to act by controlling the rate of synthesis of proteins. The primary action of the corticosteroid is to interfere with the synthesis of arachidonic acid by inhibiting the phospholipase A2 synthesis. The overall effect…

AQUAPHOR® Smith & Nephew Petrolatum Dermatological Base Indications And Clinical Uses: A neutral, anhydrous base for compounding smooth, stable emulsions; highly miscible with both aqueous solutions and other oil-based substances. For severely dry skin. Also helps promote healing of minor skin irritations. Precautions: For external use only. Avoid contact with eyes. If this occurs, rinse thoroughly with water. If rash or irritation occurs or worsens, discontinue use and consult a…

ACCUPRIL™ Parke-Davis Quinapril HCl Angiotensin Converting Enzyme Inhibitor Action And Clinical Pharmacology: Quinapril is a nonpeptide, nonsulphydryl inhibitor of angiotensin converting enzyme (ACE), which is used in the treatment of hypertension. Angiotensin converting enzyme (ACE) is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor angiotensin II. After absorption, quinapril is rapidly de-esterified to quinaprilat (quinapril diacid), its principal active metabolite. Its primary mode of action…

ACCURETIC™ Parke-Davis Quinapril HCl – Hydrochlorothiazide Angiotensin-Converting Enzyme Inhibitor – Diuretic Action And Clinical Pharmacology: Accuretic is a fixed-combination tablet which combines the antihypertensive actions of an angiotensin-converting enzyme (ACE) inhibitor, quinapril HCl, and a diuretic, hydrochlorothiazide. In clinical studies, administration of this combination produced greater reductions in blood pressure than the single agents given alone. Pharmacokinetics and Metabolism: Quinapril: Following oral administration of quinapril, peak plasma concentrations of quinapril…