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STREPTOMYCIN SULFATE™ Pfizer Aminoglycoside Antibiotic Action And Clinical Pharmacology: Streptomycin is a bactericidal antibiotic in therapeutic dosage. The mode of action is the interference with normal protein synthesis and production of “faulty proteins”. In recommended doses, Streptomycin is active against susceptible strains of many gram-negative and gram-positive organisms, and M. tuberculosis. When used alone, bacterial resistance has been shown to develop rapidly. Therefore, in the treatment of tuberculosis, it should…

STRESSTABS®, STRESSTABS® PLUS, STRESSTABS® with IRON, STRESSTABS® with ZINC Whitehall-Robins Vitamin B Complex-Ascorbic Acid-Vitamin E, Vitamin B Complex-Ascorbic Acid-Vitamin E-Selenium-Zinc-Beta Carotene, Vitamin B Complex-Ascorbic Acid-Vitamin E-Iron, Vitamin B Complex-Ascorbic Acid-Vitamin E-Zinc-Copper Dietary Supplement Indications And Clinical Uses: Stresstabs: Dietary supplement in conditions responding to therapy with B complex factors. 1nbStresstabs Plus: When physiologic stress causes severe tissue depletion of the B Complex, vitamins C, A and E. Stresstabs with Iron:…

STIEVAMYCIN® Preparations Stiefel Erythromycin–Tretinoin Topical Acne Therapy Action and Clinical Tretinoin: The precise mechanism of action of tretinoin on the skin is not fully understood. It is known that tretinoin is both pharmacologically and structurally related to vitamin A which regulates epithelial cell growth and differentiation. Tretinoin itself is known to have an irritant and keratolytic effect on the skin. These two actions which occur simultaneously have been shown histologically…

STILAMIN® Serono Somatostatin Treatment of Acute Variceal Bleeding Action and Clinical Somatostatin is a synthetic cyclic 14 amino acid peptide (identical in structure and activity to naturally occurring somatostatin) which decreases splanchnic blood flow and portal venous pressure in man, possibly through a direct action on the unstriated muscle cells mediated by a calcium-dependent mechanism. In anesthetized healthy volunteers, somatostatin–dosed as a 250 g i.v. bolus followed by a 250…

STEMETIL® Rhône-Poulenc Rorer Prochlorperazine Antipsychotic–Antiemetic Action and Clinical Prochlorperazine is a piperazine phenothiazine derivative with antipsychotic, antiemetic and weak sedative activity. Prochlorperazine has actions similar to those of other phenothiazine derivatives but appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics. However, it produces a high incidence of extrapyramidal reactions. Prochlorperazine is well absorbed from the…

STELAZINE® SmithKline Beecham Trifluoperazine HCl Antianxiety–Antiemetic–Antipsychotic Action and Clinical The mode of action of the phenothiazines has not yet been definitely established. Existing information suggests the following possibilities: Antipsychotic/antianxiety effects: Observations suggest that the primary action is to depress the physiologic accompaniments of the emotional factors of the personality which are believed to be basically evoked by the limbic system and its connections with the hypothalamus. Experimental and clinical evidence…

STERI/SOL® Warner-Lambert Consumer Healthcare Hexetidine Therapeutic Oral Rinse Indications And Clinical Uses: The symptomatic treatment of “strep” throat, tonsillitis, pharyngitis, laryngitis, gingivitis, ulcerative stomatitis, oral thrush and Vincent’s angina; postoperative hygiene following tonsillectomy, throat or oral surgery. Precautions: Avoid swallowing. Do not give to children under 12 years of age. Dosage And Administration: As a mouthwash, gargle or spray, use full strength. Apply by swab to local lesions; for buccal…

STERICIDE® Rougier Pharma Glutaraldehyde Disinfecting–Sterilizing Solution Availability And Storage: Each mL of colorless liquid with a characteristic formaldehyde odor contains: glutaraldehyde solution 2% (w/v). Bottles of 5 L. STERICIDE® Rougier Pharma Glutaraldehyde Disinfecting–Sterilizing Solution

STATEX® Paladin Morphine Sulfate Analgesic Availability And Storage: Drops: Each mL of clear, unflavored, colorless liquid contains: morphine sulfate 20 or 50 mg. Graduated bottles of 25 and 100 mL (20 mg/mL) and graduated bottles of 50 mL (50 mg/mL) with calibrated dropper. Suppositories: Each white, cone-shaped suppository contains: morphine sulfate 5, 10, 20 or 30 mg. Boxes of 10. The suppository should be placed against the rectal mucosa. The…

STADOL NS™ Bristol-Myers Squibb Butorphanol Tartrate Analgesic Action and Clinical Butorphanol acts as an agonist at kappa-opioid receptors and a mixed agonist-antagonist at mu-opioid receptors in the CNS to alter the perception of pain. The drug is believed to act at sites in the periventricular and periaqueductal gray matter, and at sites in the spinal cord.: In an animal model, the dose of butorphanol required to antagonize morphine analgesia by…