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TRIAVIL® Merck Frosst Amitriptyline HCl–Perphenazine Antidepressant–Neuroleptic Action and Clinical Triavil exerts the actions of its components. Perphenazine is a potent tranquilizer and also a potent antiemetic. Perphenazine has a nonhypnotic depressant activity on the CNS and is capable of relieving anxiety, tension, psychomotor excitement and other psychotic symptoms. Perphenazine has also widespread effects which include central and peripheral adrenergic blocking effects, anticholinergic action and loss of inhibitory control of the…

TRILAFON® Schering Perphenazine Anxiolytic–Antipsychotic–Antiemetic Indications And Clinical Uses : For use in the management of the manifestations of psychotic disorders and for the control of severe nausea and vomiting in adults. Perphenazine has not been shown effective for the management of behavioral complications in patients with mental retardation. Contra-Indications: In comatose or greatly obtunded patients and in patients receiving large doses of CNS depressants (barbiturates, alcohol, analgesics or antihistamines); in…

TRIANAL Trianon ASA–Caffeine–Butalbital Analgesic–Sedative Availability And Storage: Capsules: Each hard gelatin, oblong capsule, blue opaque cap printed “TRIANAL” and purple insert part printed, contains: butalbital USP 50 mg, caffeine USP 40 mg and ASA USP 330 mg. Nonmedicinal ingredients: cellulose and stearic acid. Alcohol-, gluten-, lactose-, sulfite- and tartrazine-free. Bottles of 100 and 500. Tablets: Each white compressed tablet embossed “TRIANAL” on one side and on the other, contains: butalbital…

TRIANAL C 1/4, C 1/2 Trianon ASA–Caffeine–Codeine Phosphate–Butalbital Analgesic–Sedative Availability And Storage: Trianal C 1/4: Each hard gelatin, oblong capsule, blue opaque cap printed “TRIANAL C 1/4” and white insert part printed, contains: butalbital USP 50 mg, caffeine USP 40 mg, ASA USP 330 mg and codeine phosphate USP 15 mg. Nonmedicinal ingredients: cellulose, croscarmellose sodium and stearic acid. Alcohol-, gluten-, lactose-, sulfite- and tartrazine-free. Bottles of 100 and 500. Trianal…

SYNACTHEN® DEPOT Novartis Pharmaceuticals Cosyntropin Zinc Hydroxide Adrenocorticotropic Hormone Action and Clinical Natural adrenocorticotropin is a straight-chain polypeptide containing 39 amino acids which, by convention, are numbered from the N terminal end of the molecule. The sequence of amino-acid occupying positions 25 to 33 varies among species and it is this part of the molecule which is most antigenic when ACTH of foreign origin is administered to man. In contrast,…

SYNAREL® Searle Nafarelin Acetate Gonadotropin Releasing Hormone (GnRH) Analogue Action and Clinical Nafarelin is an agonistic analogue of the gonadotropin releasing hormone (GnRH). Given as a single intranasal dose, nafarelin stimulates release of the pituitary gonadotropins, LH and FSH, with consequent increase of ovarian steroidogenesis. Repeated intranasal dosing abolishes the stimulatory effect on the pituitary gland. Twice daily administration of 200 g, as a nasal spray, leads to decreased secretion…

SYNALAR® Medicis Fluocinolone Acetonide Topical Corticosteroid Indications And Clinical Uses : For topical therapy of corticosteroid responsive acute and chronic skin eruptions where an anti-inflammatory, anti-allergenic, and antipruritic activity in the topical management is required. Topical solution (0.01%) is more appropriate than the fluocinolone acetonide ointment formulation for use in locations such as the scalp Contra-Indications: Untreated bacterial, tubercular, fungal and most viral lesions of the skin (including herpes simplex,…

SURMONTIL® Rhône-Poulenc Rorer Trimipramine Maleate Antidepressant Action and Clinical Trimipramine is a tricyclic antidepressant with sedative properties. It also has anticholinergic properties and potentiates the sympathetic response, presumably by blocking the reuptake of norepinephrine which has been released by the presynaptic neurons. It has a quinidine-like effect on the heart and an EEG activity similar to that of other tricyclic antidepressants.IndicationsIndications: Indications And Clinical Uses: The drug treatment of depressive…

SURGAM® SURGAM® SR Hoechst Marion Roussel Tiaprofenic Acid Anti-inflammatory–Analgesic Action and Clinical Tiaprofenic acid, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. Its mechanism of action, as with other nonsteroidal anti-inflammatory agents, is not yet completely known. Tiaprofenic acid is an inhibitor of prostaglandin synthetase enzymes which are known to be associated with inflammation and pain. The therapeutic effect of tiaprofenic acid does not…

SYMMETREL® (Antiparkinson) DuPont Pharma Amantadine HCl Antiparkinson Action and Clinical While the mechanism of action of amantadine in the treatment of Parkinson’s syndrome and drug-induced extrapyramidal reactions is not known, it is believed to release brain dopamine from nerve endings making it more available to activate dopaminergic receptors. The drug does not possess anticholinergic activity in animal tests at doses similar to those used clinically. The antiviral activity of amantadine…