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General Information Brand Name: ACCUPRIL™ Manufacturer: Parke-Davis Scientific Name: Quinapril HCl Application: Angiotensin Converting Enzyme Inhibitor Pharmacology Quinapril is a nonpeptide, nonsulphydryl inhibitor of angiotensin converting enzyme (ACE), which is used in the treatment of hypertension. Angiotensin converting enzyme (ACE) is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor angiotensin II. After absorption, quinapril is rapidly de-esterified to quinaprilat (quinapril diacid), its principal active metabolite….

General Information Brand Name: ACCURETIC™ Manufacturer: Parke-Davis Scientific Name: Quinapril HCl – Hydrochlorothiazide Application: Angiotensin-Converting Enzyme Inhibitor – Diuretic Pharmacology Accuretic is a fixed-combination tablet which combines the antihypertensive actions of an angiotensin-converting enzyme (ACE) inhibitor, quinapril HCl, and a diuretic, hydrochlorothiazide. In clinical studies, administration of this combination produced greater reductions in blood pressure than the single agents given alone. Pharmacokinetics and Metabolism: Quinapril: Following oral administration of quinapril,…

VISIPAQUE™ Nycomed Imaging A.S. Iodixanol Nonionic Radiographic Contrast Medium Action And Clinical Pharmacology: Immediately following rapid intravascular injection, iodixanol reaches peak plasma concentration and is then rapidly distributed throughout the extracellular fluid compartment. It will opacify those vessels in the path of flow of the contrast medium, permitting radiographic visualization of the vasculature of the internal structures until significant dilution and elimination occurs. The degree of density enhancement is directly…

VIQUIN FORTE® ICN Hydroquinone – Glycolic Acid Depigmentation Agent – Moisturizer Action And Clinical Pharmacology: Hyperpigmentation refers to the brown skin spots caused by an excess of the skin pigment melanin in certain areas. It can be hereditary as are freckles, caused by sun damage, occur with increasing age, or be related to pregnancy or the use of oral contraceptives. Hyperpigmentation usually develops gradually and increases with sun exposure. Skin…

VIOFORM® HYDROCORTISONE Novartis Pharmaceuticals Clioquinol – Hydrocortisone Antibacterial – Antifungal – Topical Corticosteroid Action And Clinical Pharmacology: Clioquinol, the antimicrobial component of Vioform Hydrocortisone, is active against a broad spectrum of pathogenic microorganisms, including fungi (e.g., Candida, Microsporum, Trichophyton) and gram-positive bacteria (e.g., Staphylococci). Clioquinol has only a slight inhibitory effect on gram-negative bacteria. Clioquinol exerts a bacteriostatic, rather than a bactericidal action. Hydrocortisone is a mild glucocorticoid with an…

VIOFORM® Novartis Pharmaceuticals Clioquinol Antibacterial – Antifungal Action And Clinical Pharmacology: Clioquinol is active against a broad spectrum of pathogenic microorganisms, including fungi (e.g., Candida, Microsporum, Trichophyton) and gram-positive bacteria (e.g., Staphylococci). Clioquinol has only a slight inhibitory effect on gram-negative bacteria. Clioquinol exerts a bacteriostatic, rather than a bactericidal action. The antibacterial and antifungal properties of clioquinol have long been clinically established. Topically, clioquinol has demonstrated effectiveness in secondary…

VANQUIN® Warner-Lambert Consumer Healthcare Pyrvinium Pamoate Oxyuriasis Therapy Indications And Clinical Uses: Treatment of pinworms. Contra-Indications: In patients who have previously exhibited hypersensitivity to the drug. Precautions: To forestall undue concern and help avoid accidental staining, patients and parents should be advised of the staining properties of pyrvinium. Parents and patients should be informed that pyrvinium will color the stool a bright red. This is not harmful to the patient….

VAQTA® MSD Hepatitis A Vaccine (Purified Inactivated) Vaccine Action And Clinical Pharmacology: Hepatitis A vaccine, purified inactivated is an inactivated whole virus vaccine which has been shown to induce antibody to hepatitis A virus protein. Disease Epidemiology: Hepatitis A virus is one of several hepatitis viruses that cause a systemic infection with pathology in the liver. The incubation period ranges from approximately 20 to 50 days. While the course of…

SOLAQUI ™ SOLAQUIN FORTE™ ICN Hydroquinone Demelanizing Agent Availability And Storage: Each g contains: hydroquinone USP 2% (Solaquin) or 4% (Solaquin Forte) in a vanishing, moisturizing sunscreen cream base, containing octyldimethyl PABA 5%, dioxybenzone 3% and oxybenzone 2%. Parabens-free. pH approximately 4. Tubes of 30 g. SOLAQUIN™ SOLAQUIN FORTE™ ICN Hydroquinone Demelanizing Agent

Seroquel Tablets (AstraZeneca) DESCRIPTION SEROQUEL (quetiapine fumarate) is an antipsychotic drug belonging to a new chemical class, the dibenzothiazepine derivatives. The chemical designation is 2-[2-(4-dibenzo [b,f] [1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol fumarate (2:1) (salt). It is present in tablets as the fumarate salt. All doses and tablet strengths are expressed as milligrams of base, not as fumarate salt. Its molecular formula is C 42 H 50 N 6 O 4 S 2 C 4…