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OCUFLOX™ Allergan Ofloxacin Antibacterial Agent Action And Clinical Pharmacology: The primary mechanism of action of ofloxacin appears to be the specific inhibition of DNA gyrase (topoisomerase II). This enzyme is responsible for the negative supercoiling of bacterial DNA and consequently for its topological configuration, governing functions such as RNA transcription, protein synthesis, DNA replication and repair functions. Indications And Clinical Uses: For the treatment of conjunctivitis when caused by susceptible…

OGEN® Pharmacia & Upjohn Estropipate Estrogen Action And Clinical Pharmacology: Estropipate is a natural estrogenic substance prepared from purified crystalline estrone, solubilized as the sulfate and stabilized with piperazine. It is appreciably soluble in water and has almost no odor or taste. The amount of piperazine in estropipate is not sufficient to exert a pharmacological action. Its addition ensures solubility, stability and uniform potency of the estrone sulfate. Estrogens are…

OMNI-TUSS® Rh´ne-Poulenc Rorer Codeine – Chlorpheniramine – Ephedrine – Phenyltoloxamine (Resin Complex) Antitussive – Decongestant – Expectorant Indications And Clinical Uses: To facilitate expectoration and control cough associated with inflamed mucosa and tenacious sputum which does not respond to products of lesser potency. Contra-Indications: Hypertension, cardiac disease, hyper- thyroidism, prostatic hypertrophy, sensitivity to any of the components, patients receiving MAO inhibitors. Precautions: Before prescribing medication to suppress or modify cough,…

NYTOL™, NYTOL™ Extra Strength Block Drug Diphenhydramine HCl Sleep Aid Action And Clinical Pharmacology: The primary action of diphenhydramine is the antagonism of certain effects of histamine such as broncho-constriction and capillary dilation. The most frequently encountered secondary effects of diphenhydramine are related to CNS depression. The effects vary from slight drowsiness to deep sleep and have been reported to include the inability to concentrate, lassitude, dizziness, muscular weakness and…

OCCLUSAL™ Medicis Salicylic Acid Verrucae Therapy Action And Clinical Pharmacology: Although the exact mode of action of salicylic acid in the treatment of warts is not known, its activity appears to be associated with its keratolytic action which results in mechanical removal of epidermal cells infected with wart viruses. Indications And Clinical Uses: In the treatment and removal of common warts and plantar warts. Contra-Indications: Occlusal should not be used…

OCCLUSAL™-HP Medicis Salicylic Acid Verrucae Therapy Action And Clinical Pharmacology: Although the exact mode of action of salicylic acid in the treatment of warts is not known, it activity appears to be associated with its keratolytic action which results in mechanical removal of epidermal cells infected with wart viruses. Indications And Clinical Uses: In the treatment and removal of common warts and plantar warts. Contra-Indications: Occlusal-HP should not be used…

NURSOY® Wyeth-Ayerst Soy Protein Isolate Hypoallergenic Infant Formula Indications And Clinical Uses: A nutritionally complete soy-based and milk- and lactose-free formula for common infant feeding problems associated with lactose intolerance or cow’s-milk protein sensitivity or allergy. Symptoms that may require a milk-free formula include diarrhea, vomiting, spitting up, feeding difficulties, gas, bloating, colic, and fussiness. Iron-fortified Nursoy contains vitamin A in the form of beta-carotene and has a fat blend…

NUTRISOURCE® HN Novartis Nutrition Therapeutic Nutrient Indications And Clinical Uses: A high nitrogen, complete fibre containing tube feeding (nasogastric, nasoduodenal or jejunal) for patients with normal gastrointestinal function. Recommended for both short-term and long-term tube feeding. Not recommended when a low residue tube feeding is required. Precautions: Not for parenteral administration. Dosage And Administration: 6 cans [1 500 mL or 7 520 kJ (1 800 kcal)] provides at least 100%…

NUTRISOURCE® Novartis Nutrition Therapeutic Nutrient Indications And Clinical Uses: A standard, fibre containing tube feeding (nasogastric, nasoduodenal or jejunal) for patients with normal gastrointestinal function. Recommended for both short-term and long-term tube feeding. Not recommended when a low residue tube feeding is required. Precautions: Not for parenteral administration. Dosage And Administration: 6 cans [1 500 mL or 7 520 kJ (1 800 kcal)] provides at least 100% of the Canadian…

NUTROPIN® NUTROPIN® AQ Roche Somatropin Growth Hormone Action And Clinical Pharmacology: General: Somatropin is a human growth hormone (hGH) produced by recombinant DNA technology. The amino acid sequence of the somatropin protein is identical to that of pituitary-derived human growth hormone. In vitro and in vivo preclinical testing, and clinical testing have demonstrated that somatropin is therapeutically equivalent to pituitary-derived human growth hormone in pharmacokinetics, in stimulation of linear growth…