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OSTOFORTE® Frosst Vitamin D2 (Ergocalciferol) Vitamin Indications And Clinical Uses: Treatment of refractory rickets (vitamin D-resistant rickets), familial phosphatemia and hypoparathyroidism. Contra-Indications: Hypercalcemia, malabsorption syndrome, abnormal sensitivity to the toxic effects of vitamin D, hypervitaminosis D, decreased renal function. Precautions: Hypersensitivity to vitamin D may be one etiological factor in infants with idiopathic hypercalcemia. In these cases, vitamin D must be severely restricted. Pregnancy: Safety in excess of 400 IU…

OVOL® Preparations Carter Horner Simethicone Antiflatulent Indications And Clinical Uses: Specifically for symptomatic treatment of gastrointestinal discomfort due to entrapped gas. Relief of infant colic. Symptoms And Treatment Of Overdose: Symptoms and Treatment: Treatment symptomatic. Dosage And Administration: Drops: Infants, 0.25 to 0.50 mL with or after each meal. May be added to formula or given directly from dropper. Maximum: 6 mL/24 hours. Tablets: Adults: 40 mg (2 tablets, 4…

OXEZE® TURBUHALER® Astra Formoterol Fumarate Dihydrate Bronchodilator Action And Clinical Pharmacology: Pharmacodynamics: Formoterol produces bronchodilation by stimulation of the b2-adrenergic receptors in bronchial smooth muscle, thereby causing relaxation of smooth muscle fibres. Following inhalation of formoterol, a marked improvement in pulmonary function is observed within 1 to 3 minutes and lasts for a mean duration of 12 hours after a single dose. Pharmacokinetics: Absorption: Inhaled formoterol is rapidly absorbed. Peak…

ORUDIS® ORUDIS® E ORUDIS® SR Rhône-Poulenc Rorer Ketoprofen Anti-inflammatory – Analgesic Action And Clinical Pharmacology: Animal pharmacological studies have shown that ketoprofen is a NSAID that possesses anti-inflammatory, analgesic and antipyretic properties. The anti-inflammatory action is not mediated through the pituitary adrenal axis. Its therapeutic effectiveness has been demonstrated by a reduction in joint swelling, pain and duration of morning stiffness, and by increased grip strength and an improvement in…

ORUVAIL® May & Baker Pharma Ketoprofen Anti-inflammatory – Analgesic Action And Clinical Pharmacology: Animal pharmacological studies have shown that ketoprofen possesses anti-inflammatory, analgesic and antipyretic properties. The anti-inflammatory action is not mediated through the pituitary adrenal axis. Its therapeutic effectiveness has been demonstrated by a reduction in joint swelling, pain and duration of morning stiffness, and by increased grip strength and an improvement in functional capacity. Clinical trials in patients…

OSMOVIST® Berlex Canada Iotrolan Dimeric Nonionic Radiographic Contrast Medium for Myelography Action And Clinical Pharmacology: Iotrolan is a dimeric, nonionic, hexaiodinated radiocontrast medium. The contrast-giving substance, iotrolan, is a dimer of triiodinated isophthalic acid derivatives, in which the firmly bound iodine absorbs the x-rays. Solutions of iotrolan are isotonic to plasma and cerebrospinal fluid at radiologically useful iodine levels. After intrathecal administration, iotrolan is absorbed from cerebrospinal fluid (CSF) into…

OSTAC® Roche Clodronate Disodium Bone Metabolism Regulator Action And Clinical Pharmacology: Clodronate belongs to the class of bisphosphonates which act primarily on bone. This tissue specificity is due to the high affinity of bisphosphonates for calcium phosphate crystals. Clodronate forms complexes with the hydroxyapatite of bone, altering the crystalline structure in such a way that dissolution of the crystals is inhibited. The major effect of clodronate is to inhibit osteoclast-mediated…

Bionutrix Osteonutrix: Osteonutrix is a specialized Bionutrix herbal preparation designed by physicians at Bionutrix to maximize bone health. In this premium product, Bionutrix has combined four important supplements in this special formulation as they work synergistically together to arrest cartilage deterioration and to rebuild damaged cartilage. Supportive in: Osteoarthritis – decreases pain and increases mobility in people suffering from osteoarthritis Restoring damaged bone joint tissue in osteoarthritis Tendonitis and bursitis…

ORTHOCLONE OKT® 3 Janssen-Ortho Muromonab-CD3 Immunosuppressant Action And Clinical Pharmacology: Muromonab-CD3 sterile solution is a murine monoclonal antibody to the T3 (CD3) antigen of human T cells which functions as an immunosuppressant. It is for i.v. use only. The antibody is a biochemically purified IgG2a immunoglobulin with a heavy chain of approximately 50 000 daltons and a light chain of approximately 25 000 daltons. It is directed to a glycoprotein…

ORTHO® 1/35 ORTHO® 0.5/35 ORTHO® 10/11 ORTHO® 7/7/7 Janssen-Ortho Norethindrone – Ethinyl Estradiol Oral Contraceptive Action And Clinical Pharmacology: The primary mechanism of action of this product is an inhibition of ovulation. Additionally, other effects caused by the treatment (e.g., alteration of the endometrium and the thickening of the cervical mucus), appear to interfere with implantation and conception. Indications And Clinical Uses: Conception control. Contra-Indications: History of/or actual thrombophlebitis or…