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(Page)Valuable information for over 200 common illnesses This section contains detailed and authoritative information on over 200 common illnesses. Intended for patients as well as doctors, these listings cover symptoms, risk factors, diagnostic information, and more.
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(Page)Top Stories Archive Cover Story Archive Family Practice Archive Knowing Yourself Archive The Insider Archive Cover Story Archive Asthma is a Common Problem in Children and Adults Depression is a Serious Illness, and needs Treatment Web Workshop Newer Treatments for Benign Prostatic Hyperplasia [Top] Family Practice Archive Women Are At Serious Risk [Top] Knowing Yourself Archive Hypertension or High Blood Pressure Diabetes – The New Epidemic [Top] The Insider Archive…
Zyrtec (Cetirizine)
(Pharmaceutical)ZYRTEC® UCB Pharma Cetirizine HCl Histamine H1-Receptor Antagonist Action And Clinical Pharmacology: Cetirizine, a human metabolite of hydroxyzine, is a histamine H1 receptor antagonist antiallergic compound; its principal effects are mediated via selective inhibition of peripheral H1 receptors. Cetirizine is distinguished from other histamine H1 receptor antagonists by the presence of a carboxylic acid function. This difference may be partly responsible for the selectivity of cetirizine seen in pharmacologic models…
Zovirax Oral (Acyclovir)
(Pharmaceutical)ZOVIRAX® Oral Glaxo Wellcome Acyclovir Antiviral Agent Action And Clinical Pharmacology: See Zovirax Cream. During suppression therapy there is no evidence that acyclovir prevents neural migration of the virus. It aborts episodes of recurrent herpes due to inhibition of viral replication following reactivation. Pharmacokinetics: The pharmacokinetics of acyclovir after oral administration have been evaluated in 6 clinical studies involving 110 adult patients. In one study of 35 immunocompromised patients with…
Zovirax (Acyclovir)
(Pharmaceutical)ZOVIRAX® Cream Glaxo Wellcome Acyclovir Antiviral Agent Action And Clinical Pharmacology: Acyclovir, a synthetic acyclic purine nucleoside analog, is a substrate with a high degree of specificity for herpes simplex and varicella-zoster specified thymidine kinase. Acyclovir is a poor substrate for host cell-specified thymidine kinase. Herpes simplex and varicella-zoster specified thymidine kinase transform acyclovir to its monophosphate which is then transformed by a number of cellular enzymes to acyclovir diphosphate…
Zyloprim (Allopurinol)
(Pharmaceutical)ZYLOPRIM® Glaxo Wellcome Allopurinol Xanthine Oxidase Inhibitor Action And Clinical Pharmacology: Allopurinol is a structural analogue of hypoxanthine. Reduction in both the serum and urinary uric acid levels is brought about by allopurinol inhibiting the action of xanthine oxidase, the enzyme responsible for the conversion of hypoxanthine to xanthine and xanthine to uric acid. Allopurinol is metabolized to the corresponding xanthine analogue, oxypurinol, which is also an inhibitor of xanthine…
Zypreza (Olanzapine)
(Pharmaceutical)ZYPREXA® Lilly Olanzapine Antipsychotic Action And Clinical Pharmacology: Pharmacodynamics: Olanzapine, a thienobenzodiazepine, is an antipsychotic agent, displaying high receptor affinity binding in vitro at serotonin 5-HT2A/C (Ki=4 and 11 nM, respectively), dopamine D1, D2, D3, D4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9 to 2.5 nM), adrenergic a1(Ki=19 nM), and histamine H1 (Ki=7 nM) receptors. In a behavioral paradigm predictive of antipsychotic activity, olanzapine reduced conditioned avoidance response in rats…