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OTRIVIN® Novartis Consumer Health Xylometazoline HCl Nasal Decongestant Indications And Clinical Uses: Nasal congestion in colds, rhinitis, sinusitis; also for headache, tubal block and serous otitis media associated with nasal congestion. Xylometazoline facilitates rhinoscopy and is a useful pre- and postoperative adjunct. Contra-Indications: Narrow-angle glaucoma. Concurrent therapy with MAO inhibitors. Hypersensitivity to any component. Sensitivity to even small doses of adrenergic substances as manifested by sleeplessness, dizziness, lightheadedness, weakness, tremulousness,…

OSTOFORTE® Frosst Vitamin D2 (Ergocalciferol) Vitamin Indications And Clinical Uses: Treatment of refractory rickets (vitamin D-resistant rickets), familial phosphatemia and hypoparathyroidism. Contra-Indications: Hypercalcemia, malabsorption syndrome, abnormal sensitivity to the toxic effects of vitamin D, hypervitaminosis D, decreased renal function. Precautions: Hypersensitivity to vitamin D may be one etiological factor in infants with idiopathic hypercalcemia. In these cases, vitamin D must be severely restricted. Pregnancy: Safety in excess of 400 IU…

OXEZE® TURBUHALER® Astra Formoterol Fumarate Dihydrate Bronchodilator Action And Clinical Pharmacology: Pharmacodynamics: Formoterol produces bronchodilation by stimulation of the b2-adrenergic receptors in bronchial smooth muscle, thereby causing relaxation of smooth muscle fibres. Following inhalation of formoterol, a marked improvement in pulmonary function is observed within 1 to 3 minutes and lasts for a mean duration of 12 hours after a single dose. Pharmacokinetics: Absorption: Inhaled formoterol is rapidly absorbed. Peak…

ORUDIS® ORUDIS® E ORUDIS® SR Rhône-Poulenc Rorer Ketoprofen Anti-inflammatory – Analgesic Action And Clinical Pharmacology: Animal pharmacological studies have shown that ketoprofen is a NSAID that possesses anti-inflammatory, analgesic and antipyretic properties. The anti-inflammatory action is not mediated through the pituitary adrenal axis. Its therapeutic effectiveness has been demonstrated by a reduction in joint swelling, pain and duration of morning stiffness, and by increased grip strength and an improvement in…

ORUVAIL® May & Baker Pharma Ketoprofen Anti-inflammatory – Analgesic Action And Clinical Pharmacology: Animal pharmacological studies have shown that ketoprofen possesses anti-inflammatory, analgesic and antipyretic properties. The anti-inflammatory action is not mediated through the pituitary adrenal axis. Its therapeutic effectiveness has been demonstrated by a reduction in joint swelling, pain and duration of morning stiffness, and by increased grip strength and an improvement in functional capacity. Clinical trials in patients…

OSMOVIST® Berlex Canada Iotrolan Dimeric Nonionic Radiographic Contrast Medium for Myelography Action And Clinical Pharmacology: Iotrolan is a dimeric, nonionic, hexaiodinated radiocontrast medium. The contrast-giving substance, iotrolan, is a dimer of triiodinated isophthalic acid derivatives, in which the firmly bound iodine absorbs the x-rays. Solutions of iotrolan are isotonic to plasma and cerebrospinal fluid at radiologically useful iodine levels. After intrathecal administration, iotrolan is absorbed from cerebrospinal fluid (CSF) into…

ORTHO® 1/35 ORTHO® 0.5/35 ORTHO® 10/11 ORTHO® 7/7/7 Janssen-Ortho Norethindrone – Ethinyl Estradiol Oral Contraceptive Action And Clinical Pharmacology: The primary mechanism of action of this product is an inhibition of ovulation. Additionally, other effects caused by the treatment (e.g., alteration of the endometrium and the thickening of the cervical mucus), appear to interfere with implantation and conception. Indications And Clinical Uses: Conception control. Contra-Indications: History of/or actual thrombophlebitis or…

ORTHO-NOVUM® 1/50 Janssen-Ortho Norethindrone – Mestranol Oral Contraceptive Action And Clinical Pharmacology: Acts through the mechanism of gonadotropin suppression primarily at the pituitary-ovarian axis with secondary pelvic involvement. Conception Control: The contraceptive efficacy is attributed to suppression of ovulation with a possible contribution from alterations in cervical mucus and in the endometrium. Amenorrhea: Where normal cycling does not occur, as in amenorrhea, the temporary cyclic administration of Ortho-Novum 1/50 Tablets,…

ORIFER® F Hoechst Marion Roussel Vitamins – Minerals Prenatal Supplement Indications And Clinical Uses: Dietary supplement in pregnancy; provides nutritional insurance against the common dietary deficiencies of pregnancy and postpartum. Precautions: Mild gastrointestinal upset may occur in iron-sensitive patients. The formulation is contraindicated in hemochromatosis, hemosiderosis and hemolytic anemia. Folic acid may obscure pernicious anemia in that the peripheral blood picture may return to normal while neurological manifestations remain progressive….

ORTHO® DIENESTROL Janssen-Ortho Dienestrol Vaginitis Therapy Action And Clinical Pharmacology: Dienestrol is a synthetic, nonsteroidal estrogen. The degree of systemic absorption and the mode of action are undetermined. However, one should be aware of the potential for systemic estrogen activity and related risks. Indications And Clinical Uses: The treatment of senile or atrophic vaginitis or other vaginal disturbances associated with hypoestrogenic conditions. Ortho Dienestrol cream is an estrogen product for…