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BECLODISK® BECLODISK® DISKHALER® Glaxo Wellcome Beclomethasone Dipropionate Corticosteroid for the Treatment of Bronchial Asthma Action And Clinical Pharmacology: Beclomethasone dipropionate is a potent anti-inflammatory steroid with strong topical and weak systemic activity. When inhaled at therapeutic dosages, it has a direct anti-inflammatory action on the bronchial mucosa. Since with therapeutic doses, the minute amounts absorbed do not exert any significant systemic effect, inhaled beclomethasone dipropionate can replace oral steroids with…

BECLOFORTE® Glaxo Wellcome Beclomethasone Dipropionate Corticosteroid for the Treatment of Bronchial Asthma Action And Clinical Pharmacology: Beclomethasone dipropionate is a potent anti-inflammatory steroid with strong topical and weak systemic activity. When inhaled at therapeutic dosages, it has a direct anti-inflammatory action on the bronchial mucosa. Since with therapeutic doses the minute amounts absorbed do not exert any significant systemic effect, inhaled beclomethasone dipropionate can replace oral steroids with the elimination…

BACTROBAN® SmithKline Beecham Mupirocin Topical Antibiotic Action And Clinical Pharmacology: Mupirocin exerts a bactericidal action against sensitive organisms by inhibiting bacterial protein synthesis. It reversibly and specifically binds to bacterial isoleucyl transfer-RNA synthetase Indications And Clinical Uses: For the topical treatment of the following when caused by sensitive strains of staphylococcus and streptococcus species: impetigo, superficially infected dermatoses, lesions which are moist and weeping. For abrasions, minor cuts and wounds,…

BACTRIM™ ROCHE® Roche Trimethoprim – Sulfamethoxazole Antibacterial Action And Clinical Pharmacology: Trimethoprim plus sulfamethoxazole block 2 consecutive steps in the biosynthesis of nucleic acids and proteins essential to many bacteria. Sulfamethoxazole inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid. Trimethoprim blocks the production of tetrahydrofolic acid from dihydrofolic acid by reversibly inhibiting the required enzyme, dihydrofolate reductase. The effect of the dual consecutive action is to reduce…

BARRIERE-HC® Roberts Hydrocortisone – Silicone Dermatitis Therapy Indications And Clinical Uses: Adjunctive treatment of allergic dermatoses and other inflammatory skin conditions amenable to topical corticosteroid therapy (e.g., contact, atopic and seborrheic dermatitis, neurodermatitis, psoriasis and anogenital pruritus). Contra-Indications: Tuberculous and most fungal and viral lesions of the skin, herpes simplex, vaccinia and varicella particularly. Precautions: Although untoward effects associated with the use of topical corticosteroids are uncommon and not to…

BAYCOL® Bayer Cerivastatin Sodium Lipid Metabolism Regulator Action And Clinical Pharmacology: Cerivastatin is an entirely synthetic, enantiomerically pure cholesterol-lowering agent and is structurally similar to the fungal derivatives of this therapeutic class. Cerivastatin is a competitive inhibitor of 3-hydroxy-3methyl-glutaryl-coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the conversion of HMG-CoA to mevalonate, which is an early and rate-limiting step in the biosynthesis of cholesterol. The inhibition of cholesterol biosynthesis by cerivastatin…

BCG Vaccine (Freeze Dried) Connaught Attenuated Tubercle Bacillus Active Immunizing Agent Action And Clinical Pharmacology: BCG Vaccine (Freeze-Dried) for intracutaneous administration, as prepared by Connaught Laboratories Limited, is made from a culture of an attenuated strain of living bovine tubercle bacillus (Bacillus Calmette-Gurin). It is supplied as a freeze-dried product ready for immediate use following reconstitution with the accompanying diluent, which consists of sterile phosphate-buffered saline. The manufacturing and testing…

BACTIGRAS® Smith & Nephew Chlorhexidine Acetate Topical Antibacterial Action And Clinical Pharmacology: Chlorhexidine inhibits the growth of vegetative gram-positive and gram-negative organisms in vitro. Acid fast bacilli and heat resistant bacterial spores are not susceptible to the lethal action of chlorhexidine even in strong concentrations at room temperature. Chlorhexidine has greater activity in alkaline media. Adsorption of chlorhexidine on organic matter, pus, serum, blood, etc. will cause a reduction in…

BACITRACIN Pharmacia & Upjohn Antibiotic Action And Clinical Pharmacology: Bacitracin, an antibiotic substance derived from cultures of B. subtilis (Tracey), exerts pronounced antibacterial action in vitro against a variety of gram-positive and a few gram-negative organisms. However, among systemic diseases, only staphylococcal infections qualify for consideration of bacitracin therapy. Bacitracin is assayed against a standard and its activity is expressed in units, 1 mg having a potency of not less…

BABY’S OWN™ OINTMENT Block Drug Zinc Oxide Skin Protective Indications And Clinical Uses: Prevention and relief of diaper rash. Warnings: For external use only. Avoid contact with eyes. If eye contact occurs, rinse thoroughly with water. Discontinue use if rash occurs or worsens. Keep out of the reach of children. Dosage: To relieve diaper rash apply 3 or more times daily at first sign of redness. To prevent diaper rash…