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SUPRES® Merck Frosst Methyldopa-Chlorothiazide Antihypertensive Action and Clinical Methyldopa: Methyldopa, an antihypertensive agent, is an aromatic-amino-acid decarboxylase inhibitor in animals and in man. Although the mechanism of action has yet to be conclusively demonstrated, the antihypertensive effect of methyldopa probably is due to its metabolism to alpha-methyl-norepinephrine, which then lowers arterial pressure by stimulation of central inhibitory alpha-adrenergic receptors, false neurotransmission, and/or reduction of plasma renin activity. Methyldopa has been…

SULTRIN® Janssen-Ortho Triple Sulfa Vaginitis Therapy Indications And Clinical Uses: Postoperative vaginitis or cervicitis, nonspecific vaginitis, ulcerative vaginitis and related gynecological conditions. Contra-Indications: Sulfonamide sensitivity; kidney disease. Precautions: Although some absorption of sulfonamide may occur through the vaginal mucosa, systemic reactions attributable to this are infrequent, as are local sensitivity reactions such as increased discomfort or a burning sensation following the use of this product. However, as with all sulfonamides,…

SUPRANE® AstraZeneca Desflurane Inhalation Anesthetic Action and Clinical Pharmacology: Desflurane is a volatile inhalational anesthetic whose low solubility (blood/gas partition coefficient equals 0.42) permits rapid variation in anesthetic depth. If anesthesia is maintained with inflow rates of greater than 2 L/min, the alveolar concentration is usually within 10% of the inspired concentration. It is not necessary to deliver concentrations of desflurane far in excess of the desired end-tidal concentration (“overpressurization”…

SULCRATE® SUSPENSION PLUS Hoechst Marion Roussel Sucralfate Gastroduodenal Cytoprotective Agent Action and Clinical Pharmacology: Sucralfate exerts a generalized gastric cytoprotective effect by enhancing natural mucosal defense mechanisms. Studies conducted in animals and clinical trials in humans have demonstrated that sucralfate can protect the gastric mucosa against various irritants such as alcohol, ASA, hydrochloric acid, sodium hydroxide or sodium taurocholate. In addition, sucralfate has been demonstrated to have a greater affinity…

SULFACET-R® Dermik Sulfacetamide Sodium-Sulfur Acne Therapy Indications And Clinical Uses: Severe acne vulgaris, seborrheic dermatitis, bacterial folliculitis and related conditions. Contra-Indications: Hypersensitivity to the sulfonamides as indicated by a previous toxic reaction to them (e.g. agranulocytosis, acute hemolytic anemia, purpura hemorrhagica, drug fever, jaundice, or contact dermatitis). Precautions: Sulfur may cause reddening and scaling of the epidermis, but if undue skin irritation develops or increases, discontinue use and consult a…

SULFUR SOAP Stiefel Acne Therapy Availability And Storage: Each g of neutral soap contains: precipitated sulfur USP 10%. Nonmedicinal ingredients: butylated hydroxytoluene, fragrance, purified water, soap chips and trisodium HEDTA. Bars of 75 g. SULFUR SOAP Stiefel Acne Therapy

SUCCINYLCHOLINE CHLORIDE INJECTION USP Bioniche Neuromuscular Blocking Agent Availability And Storage: Each mL of sterile solution contains: succinylcholine chloride (anhydrous base) 20 mg equivalent to dihydrate 22 mg. Nonmedicinal ingredients: hydrochloric acid (to adjust pH) and sodium chloride (for isotonicity). Ampuls of 5 mL, boxes of 10. Multiple dose vials of 10 and 20 mL (also contains methylparaben and propylparaben), trays of 10. Refrigerate (2 to 8°C) to prevent a…

SUDAFED® COLD & COUGH EXTRA STRENGTH, SUDAFED® COLD & FLU, SUDAFED® DECONGESTANT, SUDAFED® DECONGESTANT EXTRA STRENGTH, SUDAFED® DECONGESTANT 12 HOUR, SUDAFED® DECONGESTANT CHILDREN’S CHEWABLE, SUDAFED® HEAD COLD AND SINUS EXTRA STRENGTH Warner-Lambert Consumer Healthcare Pseudoephedrine HCl-Dextromethorphan HBr-Acetaminophen, Acetaminophen-Dextromethorphan HBr-Guaifenesin-Pseudoephedrine HCl, Pseudoephedrine HCl, Pseudoephedrine HCl, Pseudoephedrine HCl, Pseudoephedrine HCl, Acetaminophen-Pseudoephedrine HCl Nasal Decongestant-Antitussive-Analgesic, Analgesic-Antitussive-Expectorant-Nasal Decongestant, Nasal Decongestant, Nasal Decongestant, Nasal Decongestant, Nasal Decongestant, Analgesic-Nasal Decongestant Indications And Clinical Uses: Cold &…

SUFENTA® Janssen-Ortho Sufentanil Citrate Opioid Analgesic-Adjunct to Anesthesia Action and Clinical Pharmacology: Sufentanil is an opioid analgesic. The analgesic potency of sufentanil is approximately 5 to 7 times that of fentanyl. Dosage requirements for equianalgesic effect will be 1/5 to  1/7 those of fentanyl on a g/kg basis. Assays of histamine in patients administered sufentanil have shown no elevation in plasma histamine levels and no indication of histamine release. I.V….

SULCRATE®, SULCRATE® SUSPENSION PLUS Hoechst Marion Roussel Sucralfate Gastroduodenal Cytoprotective Agent Action and Clinical Pharmacoligy: Sucralfate exerts a generalized gastric cytoprotective effect by enhancing natural mucosal defense mechanisms. Studies conducted in animals and clinical trials in humans have demonstrated that sucralfate can protect the gastric mucosa against various irritants such as alcohol, ASA, hydrochloric acid, sodium hydroxide or sodium taurocholate. In addition, sucralfate has been demonstrated to have a greater…