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TRANSDERM-V® Novartis Pharmaceuticals Scopolamine Anti-Motion Sickness Agent Action and Clinical Scopolamine is a naturally occurring belladonna alkaloid. As a parasympatholytic agent it competitively antagonizes acetylcholine (or other direct parasympathomimetics) at the muscarinic receptor. This means that its effect can be abolished by high doses of a parasympathomimetic agent. The effect of scopolamine depends on the sensitivity of the target organs and on the size of the dose employed. The principal…

TRANSDERM-NITRO® Novartis Pharmaceuticals Nitroglycerin Transdermal Antianginal Action and Clinical The principal pharmacological action of nitroglycerin is relaxation of vascular smooth muscle, producing a vasodilator effect on both peripheral arteries and veins, with more prominent effects on the latter. Dilation of the postcapillary vessels, including large veins, promotes peripheral pooling of blood and decreases venous return to the heart, thereby reducing left ventricular end-diastolic pressure (preload). Arteriolar relaxation reduces system vascular…

TOPSYN® Medicis Fluocinonide Topical Corticosteroid Indications And Clinical Uses: For topical therapy of corticosteroid-responsive acute and chronic skin eruptions, where an anti-inflammatory, anti-allergenic and antipruritic activity in the topical management is required. Contra-Indications: Untreated bacterial, tubercular, fungal and most viral lesions of skin (including herpes simplex, vaccinia and varicella). Hypersensitivity to any of the components.WarningWarnings: Warnings in Clinical States: Pregnancy and Lactation: The safety of topical corticosteroids during pregnancy or…

TORADOL® TORADOL® IM Roche Ketorolac Tromethamine NSAID Analgesic Action and Clinical Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits analgesic activity mediated by peripheral effects. Ketorolac inhibits the synthesis of prostaglandins through inhibition of the cyclo-oxygenase enzyme system. At analgesic doses it has minimal anti-inflammatory and antipyretic activity.: Pain relief is comparable following the administration of ketorolac by i.m. or oral routes. The peak analgesic effect occurs at 2…

TRANDATE® Roberts Labetalol HCl Antihypertensive Action and Clinical Labetalol is an adrenergic receptor blocking agent possessing both alpha 1-(post-synaptic) and beta-receptor blocking activity. Its action on beta-receptors is 4 times stronger than that on alpha-receptors. It antagonizes beta 1- and beta 2-receptors equally. The mechanism of the antihypertensive action of labetalol has not been fully established. It is considered that labetalol lowers blood pressure by partially blocking the alpha-adrenoceptors in…

TRANS-PLANTAR® TRANS-VER-SAL® Westwood-Squibb Salicylic Acid Plantar Wart Therapy Verrucae Therapy Indications and Clinical Uses: Indications Trans-Plantar: For the treatment of plantar warts. Trans-Ver-•Sal: For the treatment of common wart infections. Contraindications: Should not be used by patients with diabetes or impaired blood circulation unless directed by physician. Do not use on moles, birthmarks, uro-genital warts and warts with hair. It is contraindicated for patients with a known sensitivity to any…

TONOCARD® AstraZeneca Tocainide HCl Antiarrhythmic Agent Action and Clinical Tocainide is a primary amine analog of lidocaine. Its electrophysiologic properties are similar to those of lidocaine. It possesses class IB properties in the modified electrophysiological classification of antiarrhythmic drugs proposed by Vaughan-Williams. In studies of isolated dog Purkinje fibres, tocainide in concentrations of 1 to 50 g/mL had no significant effect on resting membrane potential, but reduced the amplitude and…

TOLECTIN® Janssen-Ortho Tolmetin Sodium Anti-inflammatory–Analgesic–Antipyretic Action and Clinical Tolmetin has demonstrated anti-inflammatory, analgesic and antipyretic properties in classical animal test systems. In patients with rheumatoid arthritis, the anti-inflammatory action has been shown by a reduction in joint swelling, pain and duration of morning stiffness, as well as by enhanced grip strength, increased mobility and increased delay in the onset of fatigue. Studies in laboratory animals and man have demonstrated that…

TOMYCINE™ CIBA Vision Tobramycin Topical Antibiotic Availability And Storage: Each mL of sterile ophthalmic solution contains: tobramycin 0.3% (3 mg/mL). Nonmedicinal ingredients: benzalkonium chloride (preservative), boric acid, purified water, sodium chloride, sodium hydroxide and/or sulfuric acid (to adjust pH), sodium sulfate and tyloxapol. Plastic squeeze bottles of 5 mL. Avoid contamination of the dropper tip by avoiding contact with the eye, skin or other surfaces. Keep this bottle tightly closed…

TOBRAMYCIN Rivex Ophthalmics Antibiotic Availability And Storage: Each mL of sterile ophthalmic solution contains: tobramycin 0.3%. Nonmedicinal ingredients: benzalkonium chloride (as a preservative), boric acid, purified water, sodium chloride, sodium hydroxide, sodium sulfate, sulfuric acid and tyloxapol. Plastic squeeze bottles of 5 mL with controlled tip applicators. TOBRAMYCIN Rivex Ophthalmics Antibiotic