Seroquel Tablets (AstraZeneca) DESCRIPTION SEROQUEL (quetiapine fumarate) is an antipsychotic drug belonging to a new chemical class, the dibenzothiazepine derivatives. The chemical designation is 2-[2-(4-dibenzo [b,f] [1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol fumarate (2:1) (salt). It is present in tablets as the fumarate salt. All doses and tablet strengths are expressed as milligrams of base, not as fumarate salt. Its molecular formula is C 42 H 50 N 6 O 4 S 2 C 4…
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Seroquel (Quetiapine Fumarate)
(Pharmaceutical)Serevent Diskus (Salmeterol Xinafoate)
(Pharmaceutical)SEREVENT DISKUS DESCRIPTION SEREVENT DISKUS (salmeterol xinafoate inhalation powder) contains salmeterol xinafoate as the racemic form of the 1-hydroxy-2-naphthoic acid salt of salmeterol. The active component of the formulation is salmeterol base, a highly selective beta 2 -adrenergic bronchodilator. The chemical name of salmeterol xinafoate is 4-hydroxy-(alpha) 1 -[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol, 1-hydroxy-2-naphthalenecarboxylate. The molecular weight of salmeterol xinafoate is 603.8, and the empirical formula is C 25 H 37 NO 4 C…
Sectral (Acebutolol HCl)
(Pharmaceutical)SECTRAL DESCRIPTION Sectral (acebutolol HCl) is a selective, hydrophilic beta-adrenoreceptor blocking agent with mild intrinsic sympathomimetic activity for use in treating patients with hypertension and ventricular arrhythmias. It is marketed in capsule form for oral administration. Sectral capsules are provided in two dosage strengths which contain 200 or 400 mg of acebutolol as the hydrochloride salt. The inactive ingredients present are D&C Red 22, FD&C Blue 1, FD&C Yellow 6,…
Sedapap (Butalbital-Acetaminophen)
(Pharmaceutical)SEDAPAP DESCRIPTION Butalbital and acetaminophen is supplied in tablet form for oral administration. Butalbital (5-allyl-5-isobutylbarbituric acid), a slightly bitter, white, odorless, crystalline powder, is a short to intermediate-acting barbiturate. It has the following structural formula: C 11 H 16 N 2 O 3 MW = 224.26 Acetaminophen (4′-hydroxyacetanalide), a slightly bitter, white, odorless, crystalline powder, is a non-opiate, nonsalicylate analgesic and antipyretic. It has the following structural formula: C 8…
Semprex-D (Acrivastine-Pseudoephedrine Hydrochloride)
(Pharmaceutical)SEMPREX-D DESCRIPTION SEMPREX-D Capsules (acrivastine and pseudoephedrine hydrochloride) are a fixed combination product formulated for oral administration. Acrivastine is an antihistamine and pseudoephedrine is a decongestant. Each capsule contains 8 mg acrivastine and 60 mg pseudoephedrine hydrochloride and the inactive ingredients: lactose, magnesium stearate and sodium starch glycolate. The green and white capsule shell consists of gelatin, D&C Yellow No. 10, FD&C Green No. 3, and titanium dioxide. The yellow…
Saquinavir
(Pharmaceutical)SAQUINAVIR DESCRIPTION FORTOVASE brand of saquinavir is an inhibitor of the human immunodeficiency virus (HIV) protease. FORTOVASE is available as beige, opaque, soft gelatin capsules for oral administration in a 200-mg strength (as saquinavir free base). Each capsule also contains the inactive ingredients medium chain mono- and diglycerides, povidone and dl-alpha tocopherol. Each capsule shell contains gelatin and glycerol 85% with the following colorants: red iron oxide, yellow iron oxide…
SangCya Oral Solution
(Pharmaceutical)SANGCYA ORAL SOLUTION (SANGSTAT) WARNING Only physicians experienced in management of systemic immunosuppressive therapy for the indicated disease should prescribe SangCya® (Cyclosporine Oral Solution, USP [ MODIFIED ]). At doses used in solid organ transplantation, only physicians experienced in immunosuppressive therapy and management of organ transplant recipients should prescribe SangCya®. Patients receiving the drug should be managed in facilities equipped and staffed with adequate laboratory and supportive medical resources. The…
Sargramostim (Granulocyte-Macrophage Colony Stimulating Factor)
(Pharmaceutical)SAGRAMOSTIM (LEUKINE®) DESCRIPTION LEUKINE® (sargramostim) is a recombinant human granulocyte-macrophage colony stimulating factor (rhu GM-CSF) produced by recombinant DNA technology in a yeast (S. cerevisiae) expression system. GM-CSF is a hematopoietic growth factor which stimulates proliferation and differentiation of hematopoietic progenitor cells. LEUKINE is a glycoprotein of 127 amino acids characterized by 3 primary molecular species having molecular masses of 19,500, 16,800 and 15,500 daltons. The amino acid sequence of…
Sandoglobulin IV
(Pharmaceutical)SANDOGLOBULIN IV DESCRIPTION Immune Globulin Intravenous (Human), (IGIV) Sandoglobulin®, is a sterile, highly purified polyvalent antibody product containing in concentrated form all the IgG antibodies which regularly occur in the donor population (1). This immunoglobulin preparation is produced by cold alcohol fractionation from the plasma of volunteer US donors. Part of the fractionation may be performed by another US-licensed manufacturer. The fractionation process by which Sandoglobulin® is prepared from plasma…
Salazopyrin (Sulfasalazine)
(Pharmaceutical)SALAZOPYRIN® SALAZOPYRIN EN-TABS® Pharmacia & Upjohn Sulfasalazine Anti-inflammatory Action And Clinical Pharmacology: About 20% of sulfasalazine is absorbed in the small intestine after oral administration. A small percentage of the absorbed sulfasalazine is excreted in the urine and the rest via the bile into the small intestine (enterohepatic circulation). This portion together with the unabsorbed sulfasalazine enters the colon where it is split by bacteria into 2 main metabolites, sulfapyridine…