BONAMINE Pfizer Meclizine HCl Antiemetic Action And Clinical Pharmacology: Meclizine has antihistaminic and anticholinergic properties. The site and mechanism of action of meclizine in controlling vertigo arising from various conditions, have not been clearly defined. Pharmacological studies conducted with other antihistamines show that the peripheral labyrinthine structures may be the site of action. Indications And Clinical Uses: For prophylaxis and symptomatic relief of nausea, vomiting and vertigo associated with motion…
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Bonamine (Meclizine HCl)
(Pharmaceutical)Bicillin (Penicillin G Benzathine)
(Pharmaceutical)BICILLIN® L-A Wyeth-Ayerst Penicillin G Benzathine Antibiotic Action And Clinical Pharmacology: Actions: Penicillin G exerts a bactericidal action against penicillin-sensitive microorganisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell-wall mucopeptide. It is not active against the penicillinase-producing bacteria, which include many strains of staphylococci. Penicillin G exerts high in vitro activity against staphylococci (except penicillinase-producing strains), streptococci (Groups A,C,G,H,L and M) and pneumococci….
Bichloracetic Acid (Dichloroacetic Acid)
(Pharmaceutical)BICHLORACETIC ACID® Glenwood Dichloroacetic Acid Escharotic – Keratolytic Action And Clinical Pharmacology: Dichloroacetic acid rapidly penetrates and cauterizes skin, keratin and other tissues. Its cauterizing effect is comparable to that obtained with such methods as electrocautery or freezing. Indications And Clinical Uses: For all types of verrucae; calluses; hard and soft corns; xanthoma palpebrarum; seborrheic keratoses; ingrown nails; cysts and benign erosion of the cervix including endocervicitis; epistaxis. Contra-Indications: Should…
Bezalip (Bezafibrate)
(Pharmaceutical)BEZALIP® Roche Bezafibrate Lipid Metabolism Regulator Action And Clinical Pharmacology: The fibrates, including bezafibrate, lower elevated serum lipids by decreasing the low density lipoprotein (LDL) fraction rich in cholesterol and the very low density lipoprotein (VLDL) fraction rich in triglycerides. In addition, fibrates (including bezafibrate) increase the high density lipoprotein (HDL) cholesterol fraction. Due to their major action on lipoprotein and hepatic triglyceride lipase, the fibrates appear to produce a…
Biaxin (Clarithromycin)
(Pharmaceutical)BIAXIN® Abbott Clarithromycin Antibiotic Note: When used in combination with acid antisecretory drugs and other antimicrobials for the eradication of helicobacter pylori, the product monograph for those agents should be consulted. Action And Clinical Pharmacology: General: Clarithromycin exerts its antibacterial action by binding to the 50S ribosomal subunit of susceptible bacteria and suppressing protein synthesis. Eradication of H. pylori: H. pylori is now established as a major etiological factor in…
Betaseron (Interferon beta-1b)
(Pharmaceutical)BETASERON® Berlex Canada Interferon beta-1b Immunomodulator Action And Clinical Pharmacology: General: Interferons are a family of naturally occurring proteins, which have molecular weights ranging from 15 000 to 21 000 daltons. Three major classes of interferons have been identified: alpha, beta and gamma. Interferon beta-1b, interferon alpha, and interferon gamma have overlapping yet distinct biologic activities. The activities of interferon beta-1b are species-restricted and, therefore, the most pertinent pharmacological information…
Betaloc (Metoprolol Tartrate)
(Pharmaceutical)BETALOC® BETALOC® DURULES® Astra Metoprolol Tartrate b-Adrenoceptor Blocking Agent Action And Clinical Pharmacology: Metoprolol is a b-adrenoceptor blocking agent. In vitro and in vivo animal studies have shown that it has a preferential effect on b1-adrenoreceptors, chiefly located in cardiac muscle. This preferential effect is not absolute, however, and at higher doses, metoprolol also inhibits b2-adrenoreceptors, chiefly located in the bronchial and vascular musculature. It is used in the treatment…
Betoptic S (Betaxolol HCl)
(Pharmaceutical)BETOPTIC® S Alcon Betaxolol HCl Antiglaucoma Agent Action And Clinical Pharmacology: Betaxolol is a cardioselective (beta-1-adrenergic) receptor blocking agent. It does not have significant membrane-stabilizing (local anesthetic) activity and is devoid of intrinsic sympathomimetic action. Ocular: When instilled in the eye, betaxolol reduces elevated as well as normal intraocular pressure, whether or not accompanied by glaucoma. When used as a solution, the onset of action occurs within 30 minutes and…
Betnesol (Betamethasone)
(Pharmaceutical)BETNESOL® Preparations Roberts Betamethasone Sodium Phosphate Corticosteroid Indications And Clinical Uses: Enema: For local use as a retention enema in ulcerative colitis. Eye and Ear Drops: Inflammatory eye conditions (anterior segment) and inflammatory ear conditions, e.g., otitis externa. Tablets: Acute asthma, intractable hay fever, severe eczema, other inflammatory skin diseases; rheumatoid arthritis, nephrotic syndrome, severe ulcerative colitis, collagen diseases. Contra-Indications: Systemic infections, live virus immunization, hypersensitivity. Precautions: In patients on…
Betadine Topical (Povidone-Iodine)
(Pharmaceutical)BETADINE® Topical Preparations Purdue Frederick Povidone-Iodine Antiseptic Action And Clinical Pharmacology: Betadine is iodine complexed with povidone (polyvinyl-pyrrolidone). The compound is soluble in water forming a golden brown solution. Like iodine, the solution of the iodine complex is bactericidal, fungicidal, virucidal and trichomonacidal. However, unlike solutions of iodine, it is non-staining to natural fabrics. The antiseptic action of povidone-iodine is due to the available iodine present in the complex. Indications…