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CORTISPORIN® Glaxo Wellcome Hydrocortisone – Neomycin – Polymyxin B Compound Anti-inflammatory – Antibacterial Action And Clinical Pharmacology: Corticosteroids suppress the inflammatory response to a variety of agents and they may delay healing. Since corticosteroids may inhibit the body’s defense mechanism against infection, a concomitant antimicrobial drug may be used when this inhibition is considered to be clinically significant in a particular case. The anti-infective components in the combination are included…

CORTONE® Tablets MSD Cortisone Acetate Corticosteroid Action And Clinical Pharmacology: Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. Cortisone is a natural product of the adrenal cortex. Cortisone acetate is a synthetic steroid with the basic actions and effects of other glucocorticoids. Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency…

CORTATE® 0.5 % CORTATE® 1 % Schering Hydrocortisone Topical Corticosteroid Indications And Clinical Uses: For temporary relief of minor skin irritations, itching and rashes due to eczema, dermatitis, insect bites, poison ivy, poison oak, poison sumac, soaps, detergents, cosmetics and jewellery. Manufacturers’ Warnings In Clinical States: For external use only. Do not use in or around the eyes. Do not apply to large areas of the body. Do not use…

CORTEF® Pharmacia & Upjohn Hydrocortisone Corticosteroid Action And Clinical Pharmacology: Hydrocortisone (cortisol) is a corticosteroid secreted by the adrenal cortex. In physiologic doses, it is administered to replace deficient endogenous hormones. In larger (pharmacologic) doses, hydrocortisone decreases inflammation and suppresses the immune response. It stimulates erythroid cells of the bone marrow, prolongs survival time of erythrocytes and platelets, and produces neutrophilia and eosinopenia. Hydrocortisone promotes protein catabolism, gluconeogenesis, and redistribution…

CORTIFOAM™ R & C Hydrocortisone Acetate Rectal Anti-inflammatory Action And Clinical Pharmacology: Action appears to be due to a local anti-inflammatory effect of hydrocortisone on the mucosa rather than as a result of a systemic effect. Indications And Clinical Uses: As adjunctive therapy in the treatment of ulcerative colitis of the sigmoid colon, proctosigmoiditis, granular proctitis and ulcerative proctitis. Contra-Indications: To the use of intrarectal steroids include, obstruction, abscess, perforation,…

CORTENEMA® Axcan Pharma Hydrocortisone Glucocorticoid Indications And Clinical Uses: An adjunct in the treatment of nonspecific inflammatory diseases involving the rectum, sigmoid and left colon such as idiopathic ulcerative colitis, ulcerative proctitis, regional enteritis (granulomatous colitis) with left side involvement, proctitis, proctocolitis, and radiation proctitis. Contra-Indications: Local contraindications to the use of intrarectal steroids include obstruction, abscess, perforation, peritonitis, fresh intestinal anastomoses, extensive fistulas and sinus tracts. Active tuberculosis (active,…

BRONKAID® MISTOMETER® Sanofi Epinephrine Bronchodilator Action And Clinical Pharmacology: Epinephrine is a sympathomimetic drug that acts on both alpha and beta receptors. Indications: For temporary relief of acute paroxysms of bronchial asthma. Manufacturers’ Warnings In Clinical States: For oral inhalation only. Do not use this product unless a diagnosis of asthma has been made by a physician, if you have heart disease, high blood pressure, thyroid disease, diabetes, or difficulty…

BRADOSOL® BRADOSOL® EXTRA-STRENGTH Novartis Consumer Health Hexylresorcinol Antiseptic Indications And Clinical Uses: For the relief of sore throat. Precautions: If symptoms persist for more than 7 days, consult a physician. Dosage: 1 lozenge every 2 to 3 hours, as required. Not recommended for children under 3 years, unless on the advice of a physician. Availability And Storage: Bradosol: Each lozenge contains: hexylresorcinol 2.4 mg in a pleasant-tasting, candy-flavored base. Nonmedicinal…

BREVIBLOC® Zeneca Esmolol HCl Beta-adrenergic Receptor Blocking Agent Action And Clinical Pharmacology: Esmolol is a beta-adrenergic receptor blocking agent with predominant blocking effect on beta-1 receptors. It does not possess significant intrinsic sympathomimetic or membrane stabilizing activity. Esmolol, which is administered only i.v., has a rapid onset and a short duration of action. Pharmacodynamics: In human electrophysiology studies, esmolol produced effects typical of a beta-blocker: a decrease in the heart…

BLOCADREN® Frosst Timolol Maleate Antihypertensive – Antianginal Agent Action And Clinical Pharmacology: Timolol is a beta-adrenergic receptor blocking agent. The mechanism of the antihypertensive effect of beta- adrenergic receptor blocking agents has not yet been established. Among the factors that may be involved are: competitive ability to antagonize catecholamine-induced tachycardia at the beta receptor sites in the heart, thus decreasing cardiac output; inhibition of renin release by the kidneys; inhibition…