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TYLENOL® MENSTRUAL McNeil Consumer Healthcare Acetaminophen–Pamabrom–Pyrilamine Maleate Analgesic–Diuretic–Antihistaminic Action and Clinical The analgesic and antipyretic effects of acetaminophen are believed to be related to the inhibition of prostaglandin synthetase (a mechanism shared by ASA and related drugs). It is postulated that the analgesic effect is produced by elevation of the pain threshold and the antipyretic effect is produced through action on the hypothalamic heat-regulating centre.: Acetaminophen is considered equipotent to…

TYLENOL® ALLERGY SINUS MEDICATION McNeil Consumer Healthcare Acetaminophen–Chlorpheniramine Maleate–Pseudoephedrine HCl Analgesic–Antihistamine–Decongestant Indications And Clinical Uses: For the temporary relief of headache, sinus pain, nasal and sinus congestion, runny nose, sneezing and watery, itchy eyes due to hayfever or similar allergies. Contra-Indications: Known hypersensitivity to acetaminophen and/or pressor amines. Patients receiving or having received MAO inhibitors in the preceding 2 weeks. Although pseudoephedrine is virtually without pressor effect in normotensive patients,…

TUBERCULIN PURIFIED PROTEIN DERIVATIVE (MANTOUX)–TUBERSOL® Connaught Tuberculin Test Action and Clinical Intracutaneous tuberculin testing is an accepted aid in the diagnosis of tuberculosis infection. The reaction to intracutaneously injected tuberculin is a delayed (cellular) hypersensitivity reaction. The reaction which characteristically shows a delayed course, reaching its peak more than 24 hours after administration, consists of induration due to cell infiltration and occasionally vesiculation and necrosis. Clinically, a delayed hypersensitivity reaction…

TUBERCULIN, OLD, TINE TEST® Wyeth-Ayerst Diagnostic Test Indications And Clinical Uses: For detection of tuberculin sensitive individuals, as a determinant for additional testing (i.e., chest x-rays), and in epidemiological surveys to identify those areas having high levels of infection. Also useful in mass tuberculosis screening programs. In clinical studies covering various geographical areas and all age groups, with a total of 30 588 test subjects, there were 911 (4%) false…

TUSSIONEX® Rhône-Poulenc Rorer Hydrocodone (Resin Complex)–Phenyltoloxamine (Resin Complex) Antitussive–Antihistamine Action and Clinical Hydrocodone is a semi-synthetic narcotic antitussive and analgesic with multiple actions qualitatively similar to those of codeine. As an antitussive, hydrocodone is approximately 3 times as potent as codeine on a weight for weight basis. The precise mechanism of action of hydrocodone and other opiates is not known; however, hydrocodone is believed to inhibit coughing by interfering with…

TUMS® Tablets SmithKline Beecham Consumer Healthcare Calcium Carbonate Calcium Supplement–Antacid Availability And Storage: Regular: Each tablet contains: calcium carbonate 500 mg equivalent to elemental calcium 200 mg. Security-sealed bottles of 75, 150, 180 and rolls of 12. Regular and assorted fruit flavors. Extra: Each tablet contains: calcium carbonate 750 mg equivalent to elemental calcium 300 mg. Security-sealed bottles of 50, 100, 120, 250 and rolls of 8. Regular, assorted mint,…

TRUSOPT® Merck Frosst Dorzolamide HCl Elevated Intraocular Pressure Therapy–Topical Carbonic Anhydrase Inhibitor Action and Clinical Dorzolamide is a carbonic anhydrase inhibitor formulated for topical ophthalmic use. Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. The result is a reduction in intraocular pressure (IOP). Unlike oral carbonic anhydrase…

TRISULFAMINIC Shepherd Triple Sulfas–Phenylpropanolamine HCl Compound–Pheniramine Maleate Decongestant–Antibacterial Indications And Clinical Uses: Congestion and infection of upper respiratory tract caused by sulfa-susceptible organisms. Contra-Indications: Sensitivity to any of the components, impaired renal function, pregnancy approaching term, and in premature infants and newborn infants during the first month of life. Do not use in patients with glaucoma, prostatic hypertrophy, stenosing peptic ulcer, pyloroduodenal or bladder neck obstruction or patients receiving MAO…

TROMBOVAR® Therapex Sodium Tetradecyl Sulfate Sclerosing Agent Indications And Clinical Uses: Sclerosing treatment of varicose veins in the legs, using compression sclerotherapy. Contra-Indications: Incompetency of collateral deep veins in the legs; incompetency of the valves of the greater and lesser saphenous veins before ligation of those veins; thrombophlebitis, tuberculosis and hyperthyroidism, acute infections, prolonged recumbency; cardiac insufficiency, diabetes, arterial disease, varicosities caused by pelvic neoplasia, pregnancy. Hypersensitivity to sodium tetradecyl…

TRILISATE® Purdue Frederick Choline Magnesium Trisalicylate Anti-inflammatory–Analgesic Action and Clinical Choline magnesium trisalicylate is a combination of choline salicylate and magnesium salicylate. Choline magnesium trisalicylate is a nonsteroidal anti-inflammatory drug (NSAID) which possesses the anti-inflammatory, analgesic and antipyretic activities characteristic of salicylates. It is, however, longer acting than acetylsalicylic acid and is less likely to cause gastrointestinal bleeding. In clinical trials 6 Trilisate tablets (containing 3 g of salicylate) showed…