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TOBRADEX® Alcon Tobramycin-Dexamethasone Antibiotic-Corticosteroid Action and Clinical Uses: Dexamethasone, a potent corticosteroid, suppresses the inflammatory response to chemical, immunological or mechanical irritants. The bactericidal activity of tobramycin is accomplished by specific inhibition of normal protein synthesis in susceptible bacteria. Indications And Clinical Uses: For steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial ocular infection exist. Ocular steroids are indicated…

TIMOPTIC®, TIMOPTIC-XE® Merck Frosst Timolol Maleate Elevated Intraocular Pressure Therapy Action and Clinical Timolol is a general beta-adrenergic receptor blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant or local anesthetic (membrane-stabilizing) activity. Timolol combines reversibly with a part of the cell membrane, the beta-adrenergic receptor, and thus inhibits the usual biologic response that would occur with stimulation of that receptor. This specific competitive antagonism blocks stimulation…

TIMPILO® Merck Frosst Timolol Maleate-Pilocarpine HCl Elevated Intraocular Pressure Therapy Action and Clinical Uses: Timolol is a nonselective beta-adrenergic receptor blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane-stabilizing) activity. Timolol combines reversibly with a part of the cell membrane, the beta-adrenergic receptor, and thus inhibits the usual biologic response that would occur with stimulation of that receptor. This specific competitive antagonism blocks stimulation…

TIM-AK Dioptic Timolol Maleate Elevated Intraocular Pressure Therapy Availability And Storage: Each mL of sterile ophthalmic solution contains: timolol maleate equivalent to timolol 0.5%. Nonmedicinal ingredients: benzalkonium chloride, dibasic sodium phosphate, monobasic sodium phosphate, purified water, sodium chloride and sodium hydroxide. Plastic dropper bottles of 5 and 10 mL. Store between 15 and 30°C. Protect from light and freezing. TIM-AK Dioptic Timolol Maleate Elevated Intraocular Pressure Therapy

TIMOLIDE® Merck Frosst Timolol Maleate-Hydrochlorothiazide Antihypertensive Action and Clinical Uses: Timolide combines the antihypertensive activity of 2 agents: a beta-adrenergic receptor blocking agent (timolol maleate) and a diuretic (hydrochlorothiazide). Timolol is a non-selective beta-adrenergic receptor blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane stabilizing) activity in humans. The mechanism of the antihypertensive effect of beta-adrenergic receptor blocking agents has not yet been…

TIAZAC® Crystaal Diltiazem HCI Antihypertensive-Antianginal Action and Clinical Uses: Diltiazem is a calcium ion cellular influx inhibitor (calcium entry blocker or calcium ion antagonist).: Mechanism of Action: The therapeutic effect of this group of drugs is believed to be related to their specific cellular action of selectively inhibiting transmembrane influx of calcium ions into cardiac muscle and vascular smooth muscle. The contractile processes of these tissues are dependent upon the…

TICLID® Roche Ticlopidine HCl Inhibitor of Platelet Function Action and Clinical Uses: Ticlopidine is an inhibitor of platelet aggregation. It causes a time and dose-dependent inhibition of platelet aggregation and release of platelet factors, as well as a prolongation of bleeding time. The drug has no significant in vitro activity. The exact mechanism of action is not fully characterized, but does not involve inhibition of the prostacyclin/thromboxane pathways or platelet…

THROMBOSTAT™ Parke-Davis Thrombin (Bovine Origin) Topical Hemostatic Action and Clinical Uses: Thrombostat is a protein substance produced through a conversion reaction in which prothrombin of bovine origin is activated by tissue thromboplastin in the presence of calcium chloride. Thrombin requires no intermediate physiological agent for its action. It clots the fibrinogen of the blood directly. Failure to clot blood occurs in the rare case where the primary clotting defect is…

THYROID HORMONE Parke-Davis Desiccated Thyroid Hypothyroidism Therapy Action and Clinical Uses: The principal pharmacologic effect of exogenous thyroid hormones is to increase the metabolic rate of body tissues. The normal thyroid gland contains approximately 200 g of levothyroxine (T 4)/g of gland, and 15 g of triiodothyronine (T 3)/g. The ratio of these two hormones in the circulation does not represent the ratio in the thyroid gland, since about 80%…

THEOPHYLLINE Technilab Bronchodilator Availability And Storage: Each 15 mL of fruit-flavored elixir contains: theophylline anhydrous 80 mg. Nonmedicinal ingredients: alcohol, artificial coloring and flavorings, FD&C Yellow #6, methylparaben, natural flavoring, propylparaben, purified water, sodium benzoate, sorbitol and sucrose. Bottles of 500 mL. Store between 15 and 30°C. THEOPHYLLINE Technilab Bronchodilator