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TARKA® Knoll Trandolapril – Verapamil HCl Antihypertensive Action And Clinical Pharmacology: Tarka is a formulation containing slow-release verapamil, a phenylalkylamine calcium channel blocker, along with immediate-release trandolapril, an angiotensin converting enzyme (ACE) inhibitor. Verapamil is a calcium channel blocker that exerts its pharmacologic effects by modulating the influx of ionic calcium across the cell membrane of the arterial smooth muscle as well as in conductile and contractile myocardial cells. Verapamil…

TARO-CARBAMAZEPINE Anticonvulsant-Symptomatic Relief of Trigeminal Neuralgia-Antimanic Action and Clinical Pharmacology Carbamazepine has anticonvulsant properties which have been found useful in the treatment of partial seizures (simple or complex) with and without secondary generalization, and generalized tonic-clonic seizures. A mild psychotropic effect has been observed in some patients, which seems related to the effect of carbamazepine in localization-related epilepsies and syndromes.: Clinical Trials: Evidence supporting the efficacy of carbamazepine as an…

TAMOFEN® Rh´ne-Poulenc Rorer Tamoxifen Citrate Antineoplastic Action And Clinical Pharmacology: Tamoxifen is a nonsteroidal agent which has demonstrated potent antiestrogenic properties in animal test systems. The antiestrogenic effects are related to is ability to compete with estrogen for binding sites in target tissues such as breast and uterus. Tamoxifen inhibits the induction of rat mammary carcinoma induced by dimethylbenzanthracene (DMBA) and causes the regression of already established DMBA-induced tumors. In…

TAMONE® Pharmacia & Upjohn Tamoxifen Citrate Antineoplastic Action And Clinical Pharmacology: Tamoxifen is a nonsteroidal agent which has demonstrated potent antiestrogenic properties in animal test systems. The antiestrogenic effects are related to its ability to compete with estrogen for binding sites in target tissues such as breast and uterus. Tamoxifen inhibits the induction of rat mammary carcinoma induced by dimethylbenzanthracene (DMBA), and causes the regression of already established DMBA-induced tumors….

TANACET 125® Ashbury Biologicals/Herbal Laboratories Standardized Feverfew Migraine Prophylaxis Action And Clinical Pharmacology: Clinical trials conducted in the United Kingdom have established the effectiveness of feverfew (Tanacetum parthenium) when taken daily over a 2-month period in reducing the frequency and intensity of migraine attacks. Tanacet 125 contains specially prepared and standardized feverfew leaf (Tanacetum parthenium) which is a recognized traditional herbal remedy for several conditions, including the prevention of migraine…

TAPAZOLE® Lilly Methimazole Antithyroid Action And Clinical Pharmacology: Methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. The drug does not inactivate existing thyroxine and triiodothyronine that are stored in colloid or are circulating in the blood, nor does it interfere with the effectiveness of thyroid hormones given by mouth or by injection. The actions and use of methimazole are similar to those…

TARDAN Odan Salicylic Acid Tar Shampoo Antiseborrheic Availability And Storage: Each bottle contains: salicylic acid 2%, liquor carbonis detergens 5% and triclosan 0.3% dispersed in a blend of anionic and amphoteric surfactants, fatty acid alcanolamide and protein conditioning agents. Nonmedicinal ingredients: cocoamide DEA, disodium cocoamphodipropionate, hydrolized protein, methylcellulose, perfume, purified water and sodium lauryl sulfate. Acid pH. Plastic bottles of 250 and 500mL. TARDAN Odan Salicylic Acid-Tar Shampoo Antiseborrheic

TALWIN® Injection Sanofi Pentazocine Lactate Analgesic Action And Clinical Pharmacology: Analgesic effects: Pentazocine relieves pain of all degrees, from mild to severe, in patients with acute and chronic disorders, regardless of age or sex. Analgesia usually occurs within 15 to 30 minutes after i.m. or s.c. injection, or 2 to 3 minutes after i.v. injection, and lasts for 3 to 4 hours. A dose of 30 mg administered parenterally is…

TAMBOCOR™ 3M Pharmaceuticals Flecainide Acetate Antiarrhythmic Agent Action And Clinical Pharmacology: Flecainide belongs to the membrane stabilizing group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the 1C class of the modified Vaughan-Williams classification. It also possesses local anesthetic properties. In single cell preparations from canine cardiac tissue (Purkinje fibres) flecainide decreased the rate of rise (Vmax, Phase O) of the action potential without greatly affecting its duration; the…

T-STAT® Westwood-Squibb Erythromycin – Ethyl Alcohol Topical Anti-acne Therapy Action And Clinical Pharmacology: Ethyl alcohol is a drying and peeling agent. The mechanism of action of topically applied erythromycin in the treatment of acne vulgaris is not known. Indications And Clinical Uses: For the treatment of the inflammatory papular lesions of acne vulgaris. Not indicated for Grade IV acne. Contra-Indications: Individuals who have shown hypersensitivity to erythromycin or any of…