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TRINIPATCH® 0.2 TRINIPATCH® 0.4 TRINIPATCH® 0.6 Sanofi-Synthelabo Nitroglycerin Transdermal Delivery System Antianginal Action and Clinical The principal pharmacological action of nitroglycerin is relaxation of vascular smooth muscle, producing a vasodilator effect on both peripheral arteries and veins, with more prominent effects on the latter. Dilation of the post-capillary vessels, including large veins, promotes peripheral pooling of blood and decreases venous return to the heart, thereby reducing left ventricular end-diastolic pressure…

TRINIPATCH® 0.2 TRINIPATCH® 0.4 TRINIPATCH® 0.6 Sanofi-Synthelabo Nitroglycerin Transdermal Delivery System Antianginal Action and Clinical The principal pharmacological action of nitroglycerin is relaxation of vascular smooth muscle, producing a vasodilator effect on both peripheral arteries and veins, with more prominent effects on the latter. Dilation of the post-capillary vessels, including large veins, promotes peripheral pooling of blood and decreases venous return to the heart, thereby reducing left ventricular end-diastolic pressure…

TRIATEC-8 TRIATEC-8 STRONG TRIATEC-30 Trianon Acetaminophen–Codeine Phosphate–Caffeine Citrate Acetaminophen–Codeine Phosphate–Caffeine Citrate Acetaminophen–Codeine Phosphate Analgesic–Antipyretic–Antitussive Availability And Storage: Triatec-8: Each oblong-shaped, white tablet contains: acetaminophen 325 mg, codeine phosphate 8 mg and caffeine citrate 30 mg. Nonmedicinal ingredients: cellulose, citric acid, croscarmellose sodium, magnesium stearate and stearic acid. Alcohol-, gluten-, lactose-, sulfite- and tartrazine-free. Bottles of 30, 100 and 200. Triatec-8 Strong: Each oblong-shaped, white tablet contains: acetaminophen 500 mg, codeine…

TRIDESILON® Bayer Desonide Topical Corticosteroid Availability And Storage: Cream: Each tube and jar contains: desonide 0.05% in Acid Mantle vehicle formulated with glycerin, methylparaben, sodium lauryl sulfate, aluminum acetate, purified water, cetyl stearyl alcohol, synthetic B-wax, white petrolatum and mineral oil. Tubes of 60 g. Jars of 454 g. Ointment: Each tube contains: desonide 0.05% in white petrolatum. Tubes of 60 g. Store below 30°C. Avoid freezing. TRIDESILON® Bayer Desonide…

TRILAFON® Schering Perphenazine Anxiolytic–Antipsychotic–Antiemetic Indications And Clinical Uses : For use in the management of the manifestations of psychotic disorders and for the control of severe nausea and vomiting in adults. Perphenazine has not been shown effective for the management of behavioral complications in patients with mental retardation. Contra-Indications: In comatose or greatly obtunded patients and in patients receiving large doses of CNS depressants (barbiturates, alcohol, analgesics or antihistamines); in…

SYNACTHEN® DEPOT Novartis Pharmaceuticals Cosyntropin Zinc Hydroxide Adrenocorticotropic Hormone Action and Clinical Natural adrenocorticotropin is a straight-chain polypeptide containing 39 amino acids which, by convention, are numbered from the N terminal end of the molecule. The sequence of amino-acid occupying positions 25 to 33 varies among species and it is this part of the molecule which is most antigenic when ACTH of foreign origin is administered to man. In contrast,…

SYNALAR® Medicis Fluocinolone Acetonide Topical Corticosteroid Indications And Clinical Uses : For topical therapy of corticosteroid responsive acute and chronic skin eruptions where an anti-inflammatory, anti-allergenic, and antipruritic activity in the topical management is required. Topical solution (0.01%) is more appropriate than the fluocinolone acetonide ointment formulation for use in locations such as the scalp Contra-Indications: Untreated bacterial, tubercular, fungal and most viral lesions of the skin (including herpes simplex,…

SURMONTIL® Rhône-Poulenc Rorer Trimipramine Maleate Antidepressant Action and Clinical Trimipramine is a tricyclic antidepressant with sedative properties. It also has anticholinergic properties and potentiates the sympathetic response, presumably by blocking the reuptake of norepinephrine which has been released by the presynaptic neurons. It has a quinidine-like effect on the heart and an EEG activity similar to that of other tricyclic antidepressants.IndicationsIndications: Indications And Clinical Uses: The drug treatment of depressive…

SURGAM® SURGAM® SR Hoechst Marion Roussel Tiaprofenic Acid Anti-inflammatory–Analgesic Action and Clinical Tiaprofenic acid, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. Its mechanism of action, as with other nonsteroidal anti-inflammatory agents, is not yet completely known. Tiaprofenic acid is an inhibitor of prostaglandin synthetase enzymes which are known to be associated with inflammation and pain. The therapeutic effect of tiaprofenic acid does not…

SUPREFACT® SUPREFACT® DEPOT Hoechst Marion Roussel Buserelin Acetate Luteinizing Hormone Releasing Hormone (LH-RH) Analog Action and Clinical Buserelin is a synthetic peptide analog of the natural gonadotropin releasing hormone (GnRH/LHRH). The substitution of glycine in position 6 by D-serine, and that of glycinamide in position 10 by ethylamide, leads to a nonapeptide with a greatly enhanced LHRH effect. The effects of buserelin on follicle stimulating hormone (FSH) and luteinizing hormone…