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  CORGARD® Squibb Nadolol Antianginal – Antihypertensive Agent Action And Clinical Pharmacology: Nadolol is a noncardioselective beta-adrenergic blocking agent. It does not possess membrane stabilizing or intrinsic sympathomimetic (partial agonist) activities. The exact mechanism by which the drug exercises its anti-anginal effect is not certain. An important factor may be the reduction of myocardial oxygen requirements by blocking catecholamine-induced increases in heart rate, systolic blood pressure and the velocity and…

CORICIDIN® Cold Tablets Schering Chlorpheniramine – ASA Compound Antihistaminic – Antipyretic – Analgesic Indications And Clinical Uses: For relief of cold and flu symptoms, fever, aches and pains, accompanying a cold, relief of simple headache. Contra-Indications: Sensitivity to any of the components. Precautions: Since the depressant effects of antihistamines are additive to those of other drugs affecting the CNS, patients should be cautioned against drinking alcoholic beverages or taking hypnotics,…

COPHYLAC® Hoechst Marion Roussel Normethadone – p-Hydroxyephedrine HCl Compound Antitussive Indications And Clinical Uses: The treatment of cough associated with inflamed mucosa, which does not respond to products of lesser potency. Cophylac Expectorant is indicated to facilitate expectoration and control cough associated with inflamed mucosa and tenacious sputum which does not respond to products of lesser potency. Contra-Indications: Do not administer to patients receiving MAO inhibitors. Cophylac Expectorant is contraindicated…

CONRAY® 30 CONRAY® 43 CONRAY® 60 Mallinckrodt Iothalamate Meglumine Radiopaque Medium Action And Clinical Pharmacology: Following intravascular injection, Conray is rapidly transported through the circulatory system to the kidneys and is excreted unchanged in the urine by glomerular filtration. Renal accumulation is sufficiently rapid that maximum radiographic density in the calyces and pelves occurs in most instances about 3 to 8 minutes after injection. In patients with impaired renal function,…

COPTIN® Axcan Pharma Sulfadiazine – Trimethoprim Antibacterial Action And Clinical Pharmacology: Tetrahydrofolic acid is an essential metabolic co-factor in the biosynthesis of purines and thymine compounds which are ultimately utilized in the synthesis of DNA and RNA. The amino acids, serine and methionine, also require tetrahydrofolic acid for their biosynthesis. Cotrimazine exerts its antibacterial effect by interfering with 2 consecutive steps in the biosynthesis of tetrahydrofolic acid. Sulfadiazine inhibits bacterial…

CORDARONE® CORDARONE® I.V. Wyeth-Ayerst Amiodarone HCl Antiarrhythmic Agent Action And Clinical Pharmacology: Amiodarone is generally considered a class III antiarrhythmic drug, but it possesses electrophysiologic characteristics of all 4 Vaughan Williams classes. Like Class I drugs, amiodarone blocks sodium channels at rapid pacing frequencies, and like class II drugs, it exerts antisympathetic activity. One of its main effects, with prolonged administration, is to lengthen the cardiac action potential, a class…

COMBIVENT® Inhalation Solution Boehringer Ingelheim Ipratropium Bromide – Salbutamol Sulfate Bronchodilator Action And Clinical Pharmacology: Combivent Inhalation Solution is a combination of the anticholinergic bronchodilator, ipratropium bromide, and the beta2-adrenergic bronchodilator, salbutamol sulfate. Ipratropium bromide is a quaternary ammonium derivative of atropine and is an anticholinergic drug which has bronchodilator properties. On inhalation, the onset of action is noted within 5 to 15 minutes, with a peak response between 1…

COMPLEAT™ MODIFIED Novartis Nutrition Therapeutic Nutrient Indications And Clinical Uses: A blenderized tube feeding formulated from traditional foods including meat, vegetables and fruit for patients with normal gastrointestinal function. Recommended for both short-term and long-term tube feeding. Not recommended when a low residue tube feeding is required. Precautions: Not for parenteral administration. Dosage And Administration: 6 cans [1 500 mL or 6 700 kJ (1 600 kcal)] provides at least…

COMPLEX 15® Schering Dimethicone – Lecithin Emollient Indications And Clinical Uses: To soothe and relieve dry, sensitive skin. Phospholipid lecithin is a water-binding agent which occurs naturally in the deepest layers of the skin. Each phospholipid molecule forms a complex of 15 water molecules creating a moisture reservoir which restores the skin’s moisture balance. Dosage: Apply as often as needed to the hands, body and face. Availability And Storage: Face…

CONDYLINE™ Canderm Pharma Podofilox Antimitotic Agent Action And Clinical Pharmacology: Necrosis of visible tissue is observed following treatment of genital warts with podofilox. The exact mechanism of action is unknown. Podofilox is believed to exert its antimitotic effect by binding to tubulin, at a site close to but not identical to the binding site of colchicine; it is thought that this antimitotic effect causes necrosis of wart tissue, the observed…