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DUOVENT® UDV Boehringer Ingelheim Ipratropium Bromide – Fenoterol Hydrobromide Bronchodilator Action And Clinical Pharmacology: Duovent UDV inhalation solution is a combination of the anticholinergic bronchodilator ipratropium bromide and the beta2-adrenergic bronchodilator fenoterol hydrobromide. Ipratropium is a quaternary ammonium derivative of atropine and is an anticholinergic drug which has bronchodilator properties. On inhalation of ipratropium the onset of action is noted within 5 to 15 minutes with a peak response between…

DUPHALAC® Solvay Pharma Lactulose Crystals Laxative Action And Clinical Pharmacology: Experimental data indicate that lactulose is not significantly absorbed in the small intestine and reaches the colon essentially unchanged. There it is metabolized by bacteria with the formation of low molecular weight acids that acidify the colonic contents. Less than 2% of lactulose is absorbed systemically. Two mechanisms are believed to be involved in the laxative action of lactulose: 1)…

DRIXORAL® DAY/NIGHT Cold Relief System Schering Dexbrompheniramine – Pseudoephedrine Sulfate Antihistamine – Decongestant Indications And Clinical Uses: Symptomatic relief of upper respiratory mucosal congestion in seasonal and perennial nasal allergies, acute rhinitis and rhinosinusitis, acute and subacute sinusitis, eustachian tube blockage and secretory otitis media. Contra-Indications: Patients receiving or having received MAO inhibitors in the preceding 2 weeks; known hypersensitivity to pressor amines or antihistamines. Precautions: Although pseudoephedrine causes practically…

DRIXORAL® NASAL SOLUTION Schering Oxymetazoline HCl Nasal Decongestant Indications And Clinical Uses: The relief of congestion of the nasopharyngeal mucous membranes in a variety of allergic and infectious disorders of the upper respiratory tract, including acute rhinitis and nasopharyngitis; acute and chronic sinusitis; acute and chronic vasomotor rhinitis; perennial allergic rhinitis and seasonal allergic rhinitis (hay fever). Contra-Indications: Narrow angle glaucoma, rhinitis sicca. Concurrent therapy with MAO inhibitors. Hypersensitivity to…

DRIXORAL® N.D. Schering Pseudoephedrine Sulfate Decongestant Indications And Clinical Uses: Symptomatic relief of upper respiratory mucosal congestion in seasonal and perennial nasal allergies, acute rhinitis and rhinosinusitis, acute and subacute sinusitis, eustachian tube blockage and secretory otitis media. Contra-Indications: Patients receiving or having received MAO inhibitors in the preceding 2 weeks; known hypersensitivity to pressor amines or antihistamines. Precautions: Although pseudoephedrine causes practically no pressor effect in normotensive individuals, it…

CORICIDIN “D”® Schering Chlorpheniramine Maleate – Phenylpropanolamine Compound Antihistaminic – Decongestant – Antipyretic – Analgesic Indications And Clinical Uses: Coricidin “D”: Symptomatic relief of nasal congestion and other discomforts associated with sinusitis, colds and allergic or vasomotor rhinitis. Coricidin “D” Long Acting: For up to 12-hour relief of congestion and sneezing due to colds. Contra-Indications: Sensitivity to any of the components, patients receiving MAO inhibitors in the preceding 3 weeks….

CORICIDIN® NON-DROWSY Schering ASA – Phenylpropanolamine Analgesic – Antipyretic – Decongestant Indications And Clinical Uses: Symptomatic relief of sinus pain and congestion. Contra-Indications: Sensitivity to any of the components, patients receiving MAO inhibitors in the preceding 3 weeks. Precautions: Although phenylpropanolamine causes practically no pressor effect in normotensive individuals, it should be used with caution in patients with hypertension, diabetes, chronic lung disease, latent or clinically recognized angle closure glaucoma,…

DRISTAN® SINUS Whitehall-Robins Ibuprofen – Pseudoephedrine HCl Analgesic – Antipyretic – Nasal Decongestant Action And Clinical Pharmacology: Ibuprofen has exhibited analgesic and antipyretic activity in animal studies designed to specifically demonstrate these effects. Ibuprofen has been shown to have no glucocorticoid-like activity. Pseudoephedrine is an orally effective nasal decongestant when administered in doses of 60 mg/dose, up to 240 mg/day. In order to comply with the flexible dosing schedule approved…

DRIXORAL® DRIXTAB® Schering Dexbrompheniramine Maleate – Pseudoephedrine Sulfate Antihistamine – Decongestant Indications And Clinical Uses: Symptomatic relief of upper respiratory mucosal congestion in seasonal and perennial nasal allergies, acute rhinitis and rhinosinusitis, acute and subacute sinusitis, eustachian tube blockage and secretory otitis media. Contra-Indications: Patients receiving or having received MAO inhibitors in the preceding 2 weeks; known hypersensitivity to pressor amines or antihistamines. Children under 12 years of age (sustained…

COREG™ SmithKline Beecham Carvedilol Congestive Heart Failure Agent Action And Clinical Pharmacology: Carvedilol is a cardiovascular agent for the treatment of CHF that combines beta-adrenoceptor blockade and vasodilation in a single racemic mixture. Nonselective beta-adrenoceptor blocking activity is present in the S(-) enantiomer and alpha 1-adrenoceptor blocking activity is present at equal potency in both the R(+) and S(-) enantiomers. Carvedilol has no intrinsic sympathomimetic activity. Its action on beta-receptors…