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BACIGUENT® Johnson & Johnson• Merck Bacitracin Topical Antibiotic Indications And Clinical Uses: For the treatment and prevention of infection in minor cuts, wounds and burns. Manufacturers’ Warnings In Clinical States: For external use only. Avoid contact with eyes. If contact occurs, wash thoroughly with water. Use should be discontinued if condition worsens. No refrigeration required. Precautions: Discontinue if sensitization occurs. Prolonged use may result in the overgrowth of nonsusceptible organisms,…

ASASANTINE® Boehringer Ingelheim Dipyridamole – ASA Inhibitor of Platelet Adhesion and Aggregation Action And Clinical Pharmacology: The combined use of dipyridamole and ASA causes a significant reduction in the incidence of new fatal and nonfatal coronary events in patients with a previously documented myocardial infarction. In a randomized, double blind study, the effects of combined dipyridamole and ASA treatment were compared to ASA alone and to placebo in 2 026…

BABY’S OWN™ GRIPE WATER Block Drug Sodium Bicarbonate Compound Antacid – Antiflatulent Indications And Clinical Uses: For fast soothing relief from minor stomach upset, colic, cramps, flatulence and hiccups due to indigestion. Dosage: Shake before using. Newborn infant: 2.5 mL; 1 to 6 months: 5 mL; over 6 months: 10 mL. May be repeated up to 4 times daily as required. If symptoms persist, consult physician. Availability And Storage: Each…

ARISTOSPAN® Stiefel/Glades Triamcinolone Hexacetonide Glucocorticoid Action And Clinical Pharmacology: The hexacetonide ester of triamcinolone is relatively insoluble (0.0002% at 25°C in water). When injected intra-articularly it can be expected to be absorbed slowly from the injection site. The pharmacological action of triamcinolone hexacetonide is less intense and more prolonged, but qualitatively the same as triamcinolone acetonide. Triamcinolone hexacetonide’s activity is ascribable to the slow release of triamcinolone acetonide through hydrolysis….

ARLIDIN® ARLIDIN® FORTE Rhône-Poulenc Rorer Nylidrin HCl Peripheral Vasodilator – Organic Brain Syndrome Therapy Action And Clinical Pharmacology: Nylidrin acts predominantly by beta receptor stimulation. It has been shown to dilate arterioles in skeletal muscle and to increase cardiac output. An increase in cerebral blood flow and a decrease in vascular resistance has also been reported. The result of this combination of actions is a greater blood supply to ischemic…

ASACOL® Procter & Gamble Pharmaceuticals 5-ASA Lower Gastrointestinal Anti-inflammatory Action And Clinical Pharmacology: The active ingredient in Asacol, mesalamine (5-aminosalicylic acid, also referred to as 5-ASA), is the major active component of sulfasalazine for the treatment of inflammatory bowel disease. The available evidence suggests that mesalamine has a topical anti-inflammatory effect on the colon, where it inhibits prostaglandin and leukotriene synthesis. Asacol tablets have a special acrylic-based resin coating which…

ARTHROTEC® Searle Diclofenac Sodium – Misoprostol Anti-inflammatory – Analgesic – Mucosal Protective Agent Action And Clinical Pharmacology: Arthrotec is a combination of a nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties and a mucosal protective synthetic analog of prostaglandin E1. Arthrotec has been shown to be as effective as diclofenac in reducing the signs and symptoms of rheumatoid arthritis and osteoarthritis. In addition, Arthrotec has been associated with a lower incidence…

ARISTOCORT® Parenteral Stiefel/Glades Triamcinolone Diacetate Corticosteroid Indications And Clinical Uses: Intralesional Injection: For intralesional or sublesional use in local therapy of various skin diseases, e.g. psoriasis, alopecia areata, neurodermatitis, atopic dermatitis, acne, synovial and sebaceous cysts, pruritus ani, contact and nummular dermatoses. Not for i.v. use. Forte Parenteral: For i.m., intrasynovial or intra-articular injection. Not for i.v. use. May be used in the treatment of asthma, allergies, ulcerative colitis, collagen…

ARIMIDEX® Zeneca Anastrozole Nonsteroidal Aromatase Inhibitor Action And Clinical Pharmacology: Many breast cancers have estrogen receptors and growth of these tumors can be stimulated by estrogens. In postmenopausal women, the principal source of circulating estrogen (primarily estrone) is conversion of adrenally-generated androstenedione to estrone by aromatase in peripheral tissues, such as adipose tissue, with further conversion of estrone to estradiol. Many breast cancers also contain aromatase; the importance of tumor-generated…

ARISTOCORT® Tablets Stiefel/Glades Triamcinolone Corticosteroid Indications And Clinical Uses: Endocrine Disorders: Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone are the drugs of choice although synthetic analogs may be used in conjunction with mineralocorticoids where applicable; mineralocorticoid supplementation is of particular importance when treating this condition in infants); nonsuppurative thyroiditis; hypercalcemia associated with cancer. Rheumatic Disorders: As adjunctive therapy for short-term administration (to tide the patient over an acute episode…