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CORICIDIN® NON-DROWSY Schering ASA – Phenylpropanolamine Analgesic – Antipyretic – Decongestant Indications And Clinical Uses: Symptomatic relief of sinus pain and congestion. Contra-Indications: Sensitivity to any of the components, patients receiving MAO inhibitors in the preceding 3 weeks. Precautions: Although phenylpropanolamine causes practically no pressor effect in normotensive individuals, it should be used with caution in patients with hypertension, diabetes, chronic lung disease, latent or clinically recognized angle closure glaucoma,…

DRISTAN® SINUS Whitehall-Robins Ibuprofen – Pseudoephedrine HCl Analgesic – Antipyretic – Nasal Decongestant Action And Clinical Pharmacology: Ibuprofen has exhibited analgesic and antipyretic activity in animal studies designed to specifically demonstrate these effects. Ibuprofen has been shown to have no glucocorticoid-like activity. Pseudoephedrine is an orally effective nasal decongestant when administered in doses of 60 mg/dose, up to 240 mg/day. In order to comply with the flexible dosing schedule approved…

DRIXORAL® DRIXTAB® Schering Dexbrompheniramine Maleate – Pseudoephedrine Sulfate Antihistamine – Decongestant Indications And Clinical Uses: Symptomatic relief of upper respiratory mucosal congestion in seasonal and perennial nasal allergies, acute rhinitis and rhinosinusitis, acute and subacute sinusitis, eustachian tube blockage and secretory otitis media. Contra-Indications: Patients receiving or having received MAO inhibitors in the preceding 2 weeks; known hypersensitivity to pressor amines or antihistamines. Children under 12 years of age (sustained…

COREG™ SmithKline Beecham Carvedilol Congestive Heart Failure Agent Action And Clinical Pharmacology: Carvedilol is a cardiovascular agent for the treatment of CHF that combines beta-adrenoceptor blockade and vasodilation in a single racemic mixture. Nonselective beta-adrenoceptor blocking activity is present in the S(-) enantiomer and alpha 1-adrenoceptor blocking activity is present at equal potency in both the R(+) and S(-) enantiomers. Carvedilol has no intrinsic sympathomimetic activity. Its action on beta-receptors…

CORICIDIN® Cold Tablets Schering Chlorpheniramine – ASA Compound Antihistaminic – Antipyretic – Analgesic Indications And Clinical Uses: For relief of cold and flu symptoms, fever, aches and pains, accompanying a cold, relief of simple headache. Contra-Indications: Sensitivity to any of the components. Precautions: Since the depressant effects of antihistamines are additive to those of other drugs affecting the CNS, patients should be cautioned against drinking alcoholic beverages or taking hypnotics,…

COPHYLAC® Hoechst Marion Roussel Normethadone – p-Hydroxyephedrine HCl Compound Antitussive Indications And Clinical Uses: The treatment of cough associated with inflamed mucosa, which does not respond to products of lesser potency. Cophylac Expectorant is indicated to facilitate expectoration and control cough associated with inflamed mucosa and tenacious sputum which does not respond to products of lesser potency. Contra-Indications: Do not administer to patients receiving MAO inhibitors. Cophylac Expectorant is contraindicated…

CONRAY® 30 CONRAY® 43 CONRAY® 60 Mallinckrodt Iothalamate Meglumine Radiopaque Medium Action And Clinical Pharmacology: Following intravascular injection, Conray is rapidly transported through the circulatory system to the kidneys and is excreted unchanged in the urine by glomerular filtration. Renal accumulation is sufficiently rapid that maximum radiographic density in the calyces and pelves occurs in most instances about 3 to 8 minutes after injection. In patients with impaired renal function,…

COPTIN® Axcan Pharma Sulfadiazine – Trimethoprim Antibacterial Action And Clinical Pharmacology: Tetrahydrofolic acid is an essential metabolic co-factor in the biosynthesis of purines and thymine compounds which are ultimately utilized in the synthesis of DNA and RNA. The amino acids, serine and methionine, also require tetrahydrofolic acid for their biosynthesis. Cotrimazine exerts its antibacterial effect by interfering with 2 consecutive steps in the biosynthesis of tetrahydrofolic acid. Sulfadiazine inhibits bacterial…

CORDARONE® CORDARONE® I.V. Wyeth-Ayerst Amiodarone HCl Antiarrhythmic Agent Action And Clinical Pharmacology: Amiodarone is generally considered a class III antiarrhythmic drug, but it possesses electrophysiologic characteristics of all 4 Vaughan Williams classes. Like Class I drugs, amiodarone blocks sodium channels at rapid pacing frequencies, and like class II drugs, it exerts antisympathetic activity. One of its main effects, with prolonged administration, is to lengthen the cardiac action potential, a class…

COMBIVENT® Inhalation Solution Boehringer Ingelheim Ipratropium Bromide – Salbutamol Sulfate Bronchodilator Action And Clinical Pharmacology: Combivent Inhalation Solution is a combination of the anticholinergic bronchodilator, ipratropium bromide, and the beta2-adrenergic bronchodilator, salbutamol sulfate. Ipratropium bromide is a quaternary ammonium derivative of atropine and is an anticholinergic drug which has bronchodilator properties. On inhalation, the onset of action is noted within 5 to 15 minutes, with a peak response between 1…