Indications And Clinical Uses: In hypomagnesemic states: malnutrition, excessive gastrointestinal losses due to severe diarrhea or prolonged vomiting, malabsorption syndrome, liver cirrhosis, diabetic acidosis, chronic alcoholism, electrolyte abnormalities following the use of potent diuretics.
Contra-Indications: Renal insufficiency.
Precautions: Magnesium forms insoluble chelates with tetracyclines, thus inhibiting antibiotic absorption. Therefore, concomitant administration of magnesium and tetracyclines should be avoided.
Administer magnesium cautiously in conjunction with drugs which affect electrolyte balance: diuretics, corticosteroids, cardiovascular agents.
When barbiturates, narcotics or other CNS depressants are administered concomitantly with magnesium, their dosage should be adjusted carefully because of the additive central depressive effects of magnesium.
Prolonged administration should be conducted under close medical supervision.
Symptoms And Treatment Of Overdose: Symptoms: The absence or depression of deep tendon reflexes; drowsiness, heart block and respiratory paralysis may also occur.
Treatment: I.V. administration of 5 to 10 mEq. of calcium as gluconate (10 to 20 mL of 10% calcium gluconate) is usually adequate for reversal of heart block or respiratory depression. In extreme cases, peritoneal dialysis using a dialysate free of magnesium or hemodialysis may be necessary.
Dosage: Adults: 15 to 30 mL 1 to 3 times per day, with meals. Average dose: 15 mL 4 times per day.
Availability And Storage: Each mL of amber-yellow, transparent, raspberry-flavored solution contains: magnesium glucoheptonate 100 mg (5 mg elemental magnesium). Energy: 23.12 kJ (5.44 kcal)/5 mL. Bottles of 500 and 2 000 mL.
MAGNESIUM-ROUGIER Rougier Magnesium Glucoheptonate Magnesium Supplement