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GELFILM® Pharmacia & Upjohn Absorbable Gelatin Film Surgical Implant Description: Gelfilm Sterile Film and Gelfilm Sterile Ophthalmic Film are absorbable gelatin film approximately 0.075 mm in thickness, designed for use as an absorbable gelatin implant in neurosurgery and thoracic and ocular surgery. In the dry state absorbable gelatin film has the appearance and texture of cellophane of equivalent thickness; when moistened, it assumes a rubbery consistency and can be cut…

GARAMYCIN® Parenteral Schering Gentamicin Sulfate Antibiotic Action And Clinical Pharmacology: Gentamicin is a bactericidal antibiotic which affects bacterial growth by specific inhibition of normal protein synthesis in susceptible bacteria. It is active against a wide variety of pathogenic gram-negative and gram-positive bacteria: P. aeruginosa, Proteus species (both indole-positive and indole-negative), E. coli, K. pneumoniae, E. aerogenes, S. marcescens and Staphylococcus species (including penicillin- and methicillin-resistant strains). In addition, gentamicin sulfate…

GARAMYCIN® Topical Preparations Schering Gentamicin Sulfate Topical Antibiotic Indications And Clinical Uses: For use in the treatment of primary and secondary infections caused by sensitive strains of streptococci (Group A beta-hemolytic, alpha-hemolytic), S. aureus (coagulase positive, coagulase-negative, and some penicillinase producing strains), and the gram-negative bacteria P. aeruginosa, A. aerogenes, E. coli, P. vulgaris, and K. pneumoniae. Primary skin infections that may be expected to respond to treatment with gentamicin…

GARASONE™ Ophthalmic/Otic Preparations Schering Betamethasone Sodium Phosphate – Gentamicin Sulfate Topical Corticosteroid – Antibiotic Action And Clinical Pharmacology: The anti-inflammatory activity of betamethasone is combined with the broad spectrum bactericidal activity of gentamicin. Betamethasone inhibits the inflammatory response of the eye and ear to irritating agents of a mechanical, chemical or immunological nature, while gentamicin is active in vitro against a wide variety of pathogenic gram-negative and gram-positive bacteria Indications…

FUNGIZONE® INTRAVENOUS Squibb Amphotericin B Antifungal Indications And Clinical Uses: Amphotericin B is specifically intended for the treatment of disseminated mycotic infections, including coccidioidomycosis; cryptococcosis (torulosis); disseminated candidiasis, histoplasmosis, South American leishmaniasis, North and South American blastomycosis; mucormycosis (phycomycosis) caused by species of the genera Mucor, Rhizopus, Absidia, Entomophthora, and Basidiobolus, sporotrichosis (S. schenckii), and aspergillosis (A. fumigatus). Other Clinical Uses: Limited studies have shown that amphotericin B powder for…

FULVICIN® U/F Schering Griseofulvin (Microsize) Antifungal Antibiotic Indications And Clinical Uses: Orally effective against superficial infections caused by those fungi responsible for dermatomycoses in man and animals, namely: M. canis, M. gypseum, M. audouini, E. floccosum, T. tonsurans, T. rubrum, T. mentagrophytes, T. megninii, T. gallinae, T. verrucosum, T. sulfureum, T. interdigitale, T. schoenleinii, T. crateriform. Griseofulvin is inactive against: C. albicans (monilia), C. neoformans, B. dermatitidis, A. israelii, H….

GAMIMUNE® N Bayer Immune Globulin (Human), I.V. Passive Immunizing Agent Action And Clinical Pharmacology: Primary Humoral Immunodeficiency: Gamimune N treated with solvent/detergent supplies a broad spectrum of opsonic and neutralizing IgG antibodies for the prevention or attenuation of a wide variety of infectious diseases. Since Gamimune N is administered i.v., essentially 100% of the infused IgG antibodies are immediately available in the recipient’s circulation. Studies using a modified i.v. immunoglobulin…

GARAMYCIN® Ophthalmic/Otic Preparations Schering Gentamicin Sulfate Topical Antibiotic Action And Clinical Pharmacology: Gentamicin, an aminoglycoside antibiotic, is active against the gram-positive bacteria commonly found in eye-ear infections: coagulase-positive and coagulase-negative Staphylococci; Group A beta-hemolytic and non-hemolytic Streptococci; and Diplococcus pneumoniae. Garamicin is also active against gram-negative bacteria including P. aeruginosa, indole-positive and indole-negative Proteus species, E. coli, species of the Klebsiella-Enterobacter-Serratia group, Citrobacter species, Salmonella and Shigella, Moraxella species, Providencia…

FUCIDIN® Tablets FUCIDIN® I.V. FUCIDIN® Suspension Leo Sodium Fusidate Fusidic Acid Antibiotic Action And Clinical Pharmacology: The antibacterial action of fusidic acid results from the inhibition of bacterial protein synthesis. The drug interferes with amino acid transfer from aminoacyl-sRNA to protein on the ribosomes. Fusidic acid may be bacteriostatic or bactericidal depending on inoculum size. Although bacterial cells stop dividing almost within 2 minutes after contact with the antibiotic in…

FROBEN® FROBEN SR® Knoll Flurbiprofen Nonsteroidal Anti-inflammatory Agent Action And Clinical Pharmacology: Flurbiprofen is a nonsteroidal anti-inflammatory drug with analgesic and antipyretic activity. Although its mechanism of action has not been completely elucidated it has been shown to be an inhibitor of prostaglandin synthesis, specifically cyclo-oxygenase, and to some extent lipoxygenase, and is not due to pituitary-adrenal stimulation. Flurbiprofen is well absorbed and the rate of absorption is not altered…