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FLONASE® Glaxo Wellcome Fluticasone Propionate Corticosteroid for Nasal Use Action And Clinical Pharmacology: Fluticasone is a potent anti-inflammatory steroid with strong topical and weak systemic activity. When administered intranasally in therapeutic doses, it has a direct anti-inflammatory action on the nasal mucosa, the mechanism of which is not yet completely defined. The onset of action is not immediate, and 2 to 3 days treatment may be required before maximum relief…

FLEET ENEMA® FLEET ENEMA® Mineral Oil Johnson & Johnson Merck Sodium Phosphates Mineral Oil Laxative Action And Clinical Pharmacology: Fleet Enema: Useful as a laxative in the relief of constipation, and as a bowel evacuant for a variety of diagnostic, surgical and therapeutic indications. Dibasic sodium phosphate and monobasic sodium phosphate are poorly absorbed from the gastrointestinal tract and retain water in the lumen of the intestine. When administered rectally…

FLEET® PHOSPHO®-SODA Johnson & Johnson• Merck Sodium Phosphates Laxative Action And Clinical Pharmacology: Depending on dosage, sodium phosphates oral solution is useful as a laxative in the relief of constipation, or as a bowel evacuant for a variety of diagnostic, surgical and therapeutic indications. Dibasic sodium phosphate and monobasic sodium phosphate are poorly absorbed from the gastrointestinal tract and retain water in the lumen of the intestine. When administered orally,…

FLEXALL® Chattem Menthol Topical Analgesic Indications And Clinical Uses: For temporary relief from minor arthritis pain, bursitis, tendonitis, backache, strains and sprains. Warnings: For external use only. Keep out of the reach of children. Keep away from eyes, mucous membranes, broken or irritated skin. If rash occurs, discontinue use. Do not bandage tightly or use heating pad. Dosage: Apply generously to muscles and joints and gently massage until gel disappears….

FLEXALL® STICK Chattem Menthol – Methyl Salicylate Topical Analgesic Indications And Clinical Uses: For temporary relief from minor arthritis pain, bursitis, tendonitis, backache, strains and sprains. Manufacturers’ Warnings In Clinical States: For external use only. Keep out of the reach of children. Keep away from eyes, mucous membranes, broken or irritated skin. If rash or excessive irritation occurs, discontinue use. If condition worsens or persists for more than 7 days,…

FLAMAZINE® Smith & Nephew Silver Sulfadiazine Topical Antibacterial Action And Clinical Pharmacology: Silver sulfadiazine is released slowly from the cream, and thus rapid depletion of chloride and associated electrolyte disturbances are minimized. Silver sulfadiazine is not inhibited by PABA. In burned pigs, the absorption of silver was less than 1% of the applied dose, however 5 to 8% of the sulfadiazine was absorbed. There is very little penetration of the…

FLAMAZINE® C Smith & Nephew Silver Sulfadiazine – Chlorhexidine Digluconate Topical Antibacterial Action And Clinical Pharmacology: The mechanism of silver sulfadiazine’s antibacterial action has not been fully elucidated. After exposure to the drug, structural changes in the bacterial cell membrane occur, including distortion and enlargement of the cell and a weakening of the cell wall membrane. This is accompanied by reduced viability in sensitive strains. The silver sulfadiazine molecule dissociates…

FLAREX® Alcon Fluorometholone Acetate Corticosteroid Action And Clinical Pharmacology: Adrenocorticoids suppress the inflammatory response (edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, deposition of collagen and scar formation) to chemical, immunological or mechanical irritants. Adrenocorticoids may cause a rise in intraocular pressure in susceptible individuals. They are absorbed into aqueous humor, cornea, iris, choroid, ciliary body, and retina. Systemic absorption occurs but may be significant only at higher doses…

FLAXEDIL® Rh´ne-Poulenc Rorer Gallamine Triethiodide Muscle Relaxant Action And Clinical Pharmacology: Gallamine is a competitive neuromuscular blocking agent. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. Gallamine has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release. Following usual i.v. doses muscle relaxation occurs rapidly and reaches a…

FIORINAL® Novartis Pharmaceuticals ASA – Caffeine – Butalbital Analgesic – Sedative Indications And Clinical Uses: For tension (or muscle contraction) headache and conditions where a simultaneous sedative and analgesic action is required, such as mixed migraine headaches, menstrual and postpartum tension and pain. Contraindications, Precautions and Adverse Effects: See Fiorinal-C monograph. A possible association between Reye’s syndrome and the use of salicylates has been suggested but not established. Reye’s syndrome…