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SOTACOR® Bristol Sotalol HCl Antiarrhythmic Action and Clinical Sotalol has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. Sotalol is a racemic mixture of d-and l-sotalol. Both isomers have similar class III antiarrhythmic effects, while the l-isomer is responsible for virtually all of the beta-blocking activity. Sotalol is noncardioselective and is not associated with partial agonist or membrane stabilizing…

SOTAMOL Technilab Sotalol HCl Antiarrhythmic Availability And Storage: 80 mg: Each scored, blue caplet, engraved with TEC on one side, contains: sotalol HCl 80 mg. Nonmedicinal ingredients: colloidal silicon dioxide, cornstarch, FD&C Blue #2 aluminum lake, lactose, magnesium stearate, microcrystalline cellulose and stearic acid. Bottles of 100 and 500. 160 mg: Each scored, blue caplet, engraved with TEC on one side, contains: sotalol HCl 160 mg. Nonmedicinal ingredients: colloidal silicon…

SOLUVER® PLUS Dermtek Salicylic Acid Verrucae Therapy Availability And Storage: Each bottle contains: salicylic acid USP 27% in an acrylic vehicle. Bottles of 10 mL with brush applicator. SOLUVER® PLUS Dermtek Salicylic Acid Verrucae Therapy

SOMA® Carter Horner Carisoprodol Skeletal Muscle Relaxant Action and Clinical Carisoprodol produces muscle relaxation in animals by blocking interneuronal activity in the descending reticular formation and spinal cord. There are no peripheral or autonomic effects. Clinically, carisoprodol relieves muscle spasm and associated pain in patients with painful musculoskeletal disorders. The onset of action is rapid; effects last 4 to 6 hours. In dogs, no withdrawal symptoms occurred after abrupt cessation…

SOLUVER® Dermtek Salicylic Acid Verrucae Therapy Availability And Storage: Each bottle contains: salicylic acid USP 20% in an acrylic vehicle. Bottles of 15 mL with brush applicator. SOLUVER® Dermtek Salicylic Acid Verrucae Therapy

SOMNOL® Carter Horner Flurazepam Monohydrochloride Hypnotic Availability And Storage: 15 mg: Each white, oval, film-coated tablet, with one side imprinted Horner and the other side bisected, and imprinted 15 and mg on either side of the bisect, contains: flurazepam monohydrochloride equivalent to 15 mg of flurazepam dihydrochloride. Nonmedicinal ingredients: alumina, cellulose, FD&C Blue No. 2, lactose, magnesium stearate, polyethylene glycol, starch (corn), talc and titanium dioxide. Energy: 1.2 kJ (0.3…

SOLU-CORTEF® Pharmacia & Upjohn Hydrocortisone Sodium Succinate Glucocorticoid Action and Clinical Sterile Solu-Cortef–the highly water-soluble sodium succinate ester of hydrocortisone-permits the immediate i.v. administration of high doses of hydrocortisone in a small volume of diluent and is, therefore, particularly useful in situations where high blood levels of hydrocortisone are required rapidly. Solu-Cortef has the same metabolic and anti-inflammatory actions as hydrocortisone. When given parenterally and in equimolar quantities, the 2…

SOFRAMYCIN® Ointment SOFRAMYCIN® Ophthalmic Hoechst Marion Roussel Framycetin Sulfate-Gramicidin Framycetin Sulfate Antibiotic Action and Clinical Framycetin, a broad spectrum aminoglycoside antibiotic, is usually bactericidal in action. Although the exact mechanism of action has not been fully elucidated, the drug appears to inhibit protein synthesis in susceptible bacteria by binding to ribosomal subunits. In general, framycetin is active against many aerobic gram-negative bacteria and some aerobic gram-positive bacteria. The drug is inactive…

SOLGANAL® Schering Aurothioglucose Antirheumatic Agent Action and Clinical Although the mechanism of action is not well understood, gold compounds have been reported to decrease synovial inflammation and retard cartilage and bone destruction.: Gold is absorbed from injection sites, reaching peak concentration in blood in 4 to 6 hours. Following a single i.m. injection of 50 mg aurothioglucose suspension in each of 2 patients, peak serum levels were about 235 g/dL…

SOLGANAL Schering Aurothioglucose Antirheumatic Agent Action and Clinical Although the mechanism of action is not well understood, gold compounds have been reported to decrease synovial inflammation and retard cartilage and bone destruction.: Gold is absorbed from injection sites, reaching peak concentration in blood in 4 to 6 hours. Following a single i.m. injection of 50 mg aurothioglucose suspension in each of 2 patients, peak serum levels were about 235 g/dL…