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TRINIPATCH® 0.2 TRINIPATCH® 0.4 TRINIPATCH® 0.6 Sanofi-Synthelabo Nitroglycerin Transdermal Delivery System Antianginal Action and Clinical The principal pharmacological action of nitroglycerin is relaxation of vascular smooth muscle, producing a vasodilator effect on both peripheral arteries and veins, with more prominent effects on the latter. Dilation of the post-capillary vessels, including large veins, promotes peripheral pooling of blood and decreases venous return to the heart, thereby reducing left ventricular end-diastolic pressure…

TRINIPATCH® 0.2 TRINIPATCH® 0.4 TRINIPATCH® 0.6 Sanofi-Synthelabo Nitroglycerin Transdermal Delivery System Antianginal Action and Clinical The principal pharmacological action of nitroglycerin is relaxation of vascular smooth muscle, producing a vasodilator effect on both peripheral arteries and veins, with more prominent effects on the latter. Dilation of the post-capillary vessels, including large veins, promotes peripheral pooling of blood and decreases venous return to the heart, thereby reducing left ventricular end-diastolic pressure…

TRIATEC-8 TRIATEC-8 STRONG TRIATEC-30 Trianon Acetaminophen–Codeine Phosphate–Caffeine Citrate Acetaminophen–Codeine Phosphate–Caffeine Citrate Acetaminophen–Codeine Phosphate Analgesic–Antipyretic–Antitussive Availability And Storage: Triatec-8: Each oblong-shaped, white tablet contains: acetaminophen 325 mg, codeine phosphate 8 mg and caffeine citrate 30 mg. Nonmedicinal ingredients: cellulose, citric acid, croscarmellose sodium, magnesium stearate and stearic acid. Alcohol-, gluten-, lactose-, sulfite- and tartrazine-free. Bottles of 30, 100 and 200. Triatec-8 Strong: Each oblong-shaped, white tablet contains: acetaminophen 500 mg, codeine…

TRIAVIL® Merck Frosst Amitriptyline HCl–Perphenazine Antidepressant–Neuroleptic Action and Clinical Triavil exerts the actions of its components. Perphenazine is a potent tranquilizer and also a potent antiemetic. Perphenazine has a nonhypnotic depressant activity on the CNS and is capable of relieving anxiety, tension, psychomotor excitement and other psychotic symptoms. Perphenazine has also widespread effects which include central and peripheral adrenergic blocking effects, anticholinergic action and loss of inhibitory control of the…

TRIANAL C 1/4, C 1/2 Trianon ASA–Caffeine–Codeine Phosphate–Butalbital Analgesic–Sedative Availability And Storage: Trianal C 1/4: Each hard gelatin, oblong capsule, blue opaque cap printed “TRIANAL C 1/4” and white insert part printed, contains: butalbital USP 50 mg, caffeine USP 40 mg, ASA USP 330 mg and codeine phosphate USP 15 mg. Nonmedicinal ingredients: cellulose, croscarmellose sodium and stearic acid. Alcohol-, gluten-, lactose-, sulfite- and tartrazine-free. Bottles of 100 and 500. Trianal…

TRIATEC-30 Trianon Acetaminophen–Codeine Phosphate–Caffeine Citrate Acetaminophen–Codeine Phosphate–Caffeine Citrate Acetaminophen–Codeine Phosphate Analgesic–Antipyretic–Antitussive Availability And Storage: Triatec-8: Each oblong-shaped, white tablet contains: acetaminophen 325 mg, codeine phosphate 8 mg and caffeine citrate 30 mg. Nonmedicinal ingredients: cellulose, citric acid, croscarmellose sodium, magnesium stearate and stearic acid. Alcohol-, gluten-, lactose-, sulfite- and tartrazine-free. Bottles of 30, 100 and 200. Triatec-8 Strong: Each oblong-shaped, white tablet contains: acetaminophen 500 mg, codeine phosphate 8 mg…

SYNACTHEN® DEPOT Novartis Pharmaceuticals Cosyntropin Zinc Hydroxide Adrenocorticotropic Hormone Action and Clinical Natural adrenocorticotropin is a straight-chain polypeptide containing 39 amino acids which, by convention, are numbered from the N terminal end of the molecule. The sequence of amino-acid occupying positions 25 to 33 varies among species and it is this part of the molecule which is most antigenic when ACTH of foreign origin is administered to man. In contrast,…

SYNALAR® Medicis Fluocinolone Acetonide Topical Corticosteroid Indications And Clinical Uses : For topical therapy of corticosteroid responsive acute and chronic skin eruptions where an anti-inflammatory, anti-allergenic, and antipruritic activity in the topical management is required. Topical solution (0.01%) is more appropriate than the fluocinolone acetonide ointment formulation for use in locations such as the scalp Contra-Indications: Untreated bacterial, tubercular, fungal and most viral lesions of the skin (including herpes simplex,…

SURGAM® SURGAM® SR Hoechst Marion Roussel Tiaprofenic Acid Anti-inflammatory–Analgesic Action and Clinical Tiaprofenic acid, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. Its mechanism of action, as with other nonsteroidal anti-inflammatory agents, is not yet completely known. Tiaprofenic acid is an inhibitor of prostaglandin synthetase enzymes which are known to be associated with inflammation and pain. The therapeutic effect of tiaprofenic acid does not…

SYMMETREL® (Antiparkinson) DuPont Pharma Amantadine HCl Antiparkinson Action and Clinical While the mechanism of action of amantadine in the treatment of Parkinson’s syndrome and drug-induced extrapyramidal reactions is not known, it is believed to release brain dopamine from nerve endings making it more available to activate dopaminergic receptors. The drug does not possess anticholinergic activity in animal tests at doses similar to those used clinically. The antiviral activity of amantadine…