Hand, Foot and Mouth Disease

Medically reviewed by . Last updated on January 21, 2025

General Illness Information


Common Name:

HAND, FOOT AND MOUTH DISEASE

Medical Term: COXSACKIE VIRUS A-16 INFECTION

Description: It is a viral illness presenting with ulcers in the mouth and water blisters or red spots on palms, soles of feet and in groin and buttock area.
Mainly occurs in children from 6 months to 4 years.

Causes: Coxsackie Virus A-16 Infection

Prevention:

Prevent exposure of infants and young children to anyone with a respiratory illness. Incubation period is 3 to 6 days.

Signs & Symptoms

  • Sudden fever;
  • Sore throat with blisters and ulcers in the mouth and throat lining;
  • Headache;
  • Rash with blisters on the hands, feet and groin;
  • Appetite loss;
  • Abdominal pain (sometimes).

Risk Factors

Summer and fall seasons.

Diagnosis & Treatment

  • This disorder has a mild course and the child can be cared for at home;
  • Boil eating utensils and other items that touch the mouth of saliva or use disposable utensils to avoid transmitting the disease;
  • Boil bottle nipples separately for 20 minutes before sterilizing formula in bottles.

Medications:

To reduce high fever or for pain, you may use non-prescription drugs such as acetaminophen. Antibiotics are not effective against this disease.

Activity:

  • Keep the child in bed until fever and other symptoms disappear. Normal activities may be resumed gradually;
  • Avoid citrus, salty, spicy foods;
  • Avoid foods that need much chewing;
  • Offer soft diet – custard, gelatin, ice cream;
  • Encourage plenty of clear fluids eg. cold drinks, popsicles, sherberts;
  • Have the child rinse mouth with warm water after meals.

Possible Complications :

Dehydration from child refusing fluids.

Prognosis

  • Spontaneous recovery;
  • Fever and discomfort last for 3-4 days;
  • Mouth ulcers resolve in 7 days.

About

Chris Schwerdt, PharmD is a clinical pharmacist with over two decades of experience in long-term care, pharmacy operations, and regulatory consulting. He has led closed-door pharmacy businesses and serves on Pharmacy & Therapeutics committees for both industry and government programs. His work focuses on medication policy development, formulary strategy, and optimizing patient care through drug utilization review. Chris is affiliated with ASCP, ASHP, and the National Association of Boards of Pharmacy.