Enfalac Pregestimil (Protein Hydrolysate Formula)

Medically reviewed by . Last updated on April 7, 2025

ENFALAC PREGESTIMIL®

Mead Johnson

Protein Hydrolysate Formula

Pediatric Elemental Diet

Indications And Clinical Uses: For feeding of infants and children with malabsorption problems which may include: disaccharidase deficiency (relative or absolute), idiopathic defects in digestion or absorption, steatorrhea, cystic fibrosis, food allergies and intestinal resection.

Precautions: Patients with lengthy episodes of diarrhea and/or receiving antibiotics may require supplemental vitamin K. In a few instances, premature infants and infants with long-standing malabsorption problems have been reported to have a metabolic acidosis when receiving a casein hydrolysate formula for an extended period of time. The etiology of this acidosis is obscure. The overall incidence is rare and can be satisfactorily controlled by giving the patient 2 to 3 mEq/kg/day of sodium bicarbonate, which may be conveniently added to the formula.

Dosage: Mix with water: normal dilution – 1 packed level measuring scoop (9 g) of powder/60 mL of water. Provides a solution supplying 84 kJ (20 kcal)/30 mL. Initial feedings should be diluted to 10 kcal/30 mL or less and gradually increased to 84 kJ (20 kcal)/30 mL over a period of 3 to 5 days.

Availability And Storage: A hypoallergenic, powdered formula containing: corn syrup solids, hydrolyzed casein, modified cornstarch, medium chain triglycerides, corn oil, high oleic safflower oil, soy oil and essential vitamins and minerals. Cans of 454 g with accompanying measuring scoop. Also available for hospitals: presterilized disposable Nursette bottles of 100 mL, energy: 84 kJ (20 kcal)/30 mL.

ENFALAC PREGESTIMIL® Mead Johnson Protein Hydrolysate Formula Pediatric Elemental Diet


About

Chris Schwerdt, PharmD is a clinical pharmacist with over two decades of experience in long-term care, pharmacy operations, and regulatory consulting. He has led closed-door pharmacy businesses and serves on Pharmacy & Therapeutics committees for both industry and government programs. His work focuses on medication policy development, formulary strategy, and optimizing patient care through drug utilization review. Chris is affiliated with ASCP, ASHP, and the National Association of Boards of Pharmacy.

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