Hoechst Marion Roussel
Action And Clinical Pharmacology: Pseudoephedrine has been shown to have a similar action on the human nasal mucosa to ephedrine. It is an effective nasal decongestant and bronchodilator. Decongestion of the nasal mucosa occurs through vasoconstriction, and the relief of obstructed air passages by a direct action on the smooth muscle of the bronchi. The vasopressor effect of pseudoephedrine is less than that of ephedrine.
Indications And Clinical Uses: For conditions of acute coryza, sinusitis, and vasomotor or allergic rhinitis, by providing temporary nasal and sinus decongestion. It may also be used as an adjunct to antibiotics, antihistamines, analgesics and antitussives in the treatment of above conditions.
Contra-Indications: Patients receiving or having received MAO inhibitors in the preceding 3 weeks; known hypersensitivity to pressor amines.
Precautions: It should be used with caution in hypertensive and diabetic patients; patients with latent or clinically recognized angle closure glaucoma, coronary artery disease, congestive heart failure, prostatic hypertrophy, hyperthyroidism, urinary retention.
Adverse Reactions: As with other sympathomimetic amines, headache, dizziness, insomnia, tremor, confusion, CNS stimulation, muscular weakness, dry mouth, nausea, vomiting, difficulty in micturition, palpitations, tightness in the chest and syncope have been encountered.
Symptoms And Treatment Of Overdose: Symptoms: Increase in pulse and respiratory rate, signs of CNS stimulation, disorientation, headache, dry mouth, nausea and vomiting.
Treatment: Gastric lavage, repeated, if necessary. Acidify the urine and institute general supportive measures. If CNS excitement is prominent, a short acting barbiturate may be used.
Dosage: Adults and children over 12 years of age, one 120 mg caplet orally every 12 hours as directed by a physician. Avoid use for prolonged period of time except on the advice of a physician. Do not exceed recommended dosage.
Availability And Storage: Each white caplet, engraved ‘ELTOR’ on one side contains: pseudoephedrine HCl 120 mg in specially formulated pellets designed to provide a continuous release of the active therapeutic agent over a 12 hour period. Nonmedicinal ingredients: colloidal silicon dioxide, hydroxypropyl methylcellulose, magnesium stearate, methylcellulose, sucrose and water. Packages of 12 and 24.
ELTOR® 120 Hoechst Marion Roussel Pseudoephedrine HCl Nasal Decongestant