Brompheniramine Maleate – Guaifenesin – Phenylephrine HCl – Phenylpropanolamine HCl
Antihistamine – Expectorant – Decongestant
Indications And Clinical Uses: For the temporary relief of coughing and the complications of allergy states, including perennial and seasonal allergic rhinitis. In addition, indicated for the symptomatic relief of cough, nasal congestion and runny nose accompanying the common cold and other respiratory tract infections.
Contra-Indications: Hypersensitivity to any of the components; patients receiving MAO inhibitors.
Precautions: Before prescribing medication to suppress or modify cough, it is important to ascertain that the underlying cause of the cough is identified, that modification of the cough does not increase the risk of clinical or physiologic complications, and that appropriate therapy for the primary disease is provided.
Administer with caution to patients with cardiac or peripheral vascular disease, glaucoma, hyperthyroidism, diabetes mellitus or hypertension, chronic lung disease or shortness of breath, prostate enlargement and bladder neck obstruction and in pregnancy or lactation.
Occupational Hazards: Patients should be cautioned not to operate vehicles or hazardous machinery until their response to the drug has been determined. Since the depressant effects of antihistamines are additive to those of other drugs affecting the CNS, patients should be cautioned against drinking alcoholic beverages or taking hypnotics, sedatives, psychotherapeutic agents or other drugs with CNS depressant effects during antihistaminic therapy.
Guaifenesin has been shown to produce a color interference with certain clinical laboratory determinations of 5-hydroxyindoleacetic acid (5-HIAA) and vanillylmandelic acid (VMA).
Adverse Reactions: Hypersensitivity reactions to brompheniramine maleate, including skin rashes, urticaria, hypotension and thrombocytopenia may occur rarely. Drowsiness, lassitude, nausea, giddiness, dryness of the mouth, mydriasis, increased irritability or excitement may be encountered.
Symptoms And Treatment Of Overdose: Symptoms and Treatment: No specific therapy. Treatment should be symptomatic and supportive.
Dosage: Adults: 5 to 10 mL 4 times a day. Children 6 to 12 years: 2.5 to 5 mL 3 or 4 times a day. Children under 6 years: Consult a physician.
Availability And Storage: Each 5 mL of pale red liquid, menthol and raspberry taste and odor, contains: brompheniramine maleate 2 mg, guaifenesin 100 mg, phenylephrine HCl 5 mg and phenylpropanolamine HCl 5 mg. Nonmedicinal ingredients: alcohol, caramel color, citric acid, flavors, FD&C Red No. 40, glycerin, invert sugar, sodium benzoate, water. Energy: 15.27 kJ (3.65 kcal). Sodium:
DIMETANE® EXPECTORANT Whitehall-Robins Brompheniramine Maleate – Guaifenesin – Phenylephrine HCl – Phenylpropanolamine HCl Antihistamine – Expectorant – Decongestant