Amino (Amino Acids – Sodium Propionate – Urea)



Amino Acids – Sodium Propionate – Urea

Cervical Therapy

Action And Clinical Pharmacology: Methionine and cystine are amino-acids necessary for wound healing and forming of epithelial tissue.

Inositol acts as an essential growth factor and promotes epithelialization.

Urea aids in debridement, dissolves the coagulum and promotes epithelialization. Its solvent action on fibroblasts prevents the formation of excessive tissue, thus preventing stenosis when used as directed.

Benzalkonium chloride serves to lower surface tension and thus aids in spreading the medication. Along with sodium propionate it also exerts a bacteriostatic effect.

Amino-Cerv is geared to the higher pH of the healthy cervix in contrast with pH 4 vaginal preparations. With its pH factor of 5.5 it promotes faster healing of the cervix, yet will not adversely affect a healthy vagina.

Indications And Clinical Uses: For cervical treatment: cervicitis (mild), postpartum cervicitis, postpartum cervical tears and post surgical cervical procedures.

Contra-Indications: Deleterious side effects have not been a problem at the doses recommended. The usual precautions against allergic reactions should be observed.

Dosage And Administration: When immediate postpartum bleeding has subsided (usually from 24 to 48 hours after delivery), 1 Milex-Jector full of cream should be applied nightly for 4 weeks. In mild cervicitis (not requiring cautery or cryosurgery), 1 applicatorful of cream should be injected into the vagina nightly upon retiring for 2 weeks. A small amount should be applied immediately following a surgical cervical procedure with the exception of a cold coning procedure. One applicatorful should be injected nightly upon retiring for 2 to 4 weeks (the duration of treatment depends on extent of the surgical procedure). In each of the post surgical visits, the physician should again apply a small amount of the cream with a probe or applicator. The canal is to be completely probed on the last visit.

After cold coning, 1 applicatorful should be injected upon retiring about 24 hours after surgery and nightly thereafter for 4 weeks. During the 4 weekly office visits following cold coning, a small amount of cream should be applied with a probe or applicator into the canal by the physician. The canal is to be completely probed on the last visit.

Reasons for Variation of Directions: After most surgical procedures, cauterization, cryosurgery and laser surgery, immediate use of Amino-Cerv is indicated to aid in dissolving dead or burned tissue.

After cold coning, there is no dead tissue to slough off. Therefore, a wait of 24 hours or longer is desirable for normal healing to take place and for some fibroblasts to be laid down before applying the Amino-Cerv (which has a solvent action on both the fibroblasts and the absorbable sutures). When nonabsorbable sutures are used, Amino-Cerv can be used immediately.

Availability And Storage: Each g of cream contains: urea 8.34%, sodium propionate 0.5%, methionine 0.83%, cystine 0.35%, inositol 0.83% and benzalkonium chloride buffered to pH of 5.5 in a water-miscible cream base. Tubes of 78 g with or without Milex-Jector (2 weeks’ supply, 14 applications). Tubes of 142 g with Milex-Jector (4 weeks’ supply, 28 applications) – hospital use only. Store at room temperature.

AMINO-CERV Milex Amino Acids – Sodium Propionate – Urea Cervical Therapy

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Connected Diseases :


General Illness Information Common Name: Cervicitis Medical Term: None Specified. Description: Inflammation or infection of the cervix. There are two types, and either may be…