Claudication

Medically reviewed by . Last updated on March 1, 2025

General Illness Information


Common Name:

Claudication

Medical Term: Claudication

Description: Muscle fatigue and pain in an extremity, after a period of minimal exertion. Resting the extremity always relieves this. Repeating a similar exercise can reproduce the pain. It is more common in the lower extremity.

Causes: Blockage of an artery in the affected area.

Prevention:

  • Stop smoking;
  • Lose weight, if obese;
  • Routine exercise program;
  • Minimize the amount of saturated fats in the diet;
  • Reduction of cholesterol levels.

Diagnosis & Treatment

  • Diminished or absent pulse;
  • Reduced blood pressure at the ankle- usually the pressure at the ankle is 90% of the pressure at the arm flow but with severe narrowing it may be less than 50%;
  • Diagnosis can be confirmed by tests, such as Doppler ultrasound, color Doppler and angiography;
  • Color Doppler is a more sophisticated ultrasound technique producing a picture of the artery, showing different flow rates in different colors. This test is used much more frequently than angiography because it does not require an injection of radio-opaque dye.

General Measures:

  • Stop Smoking;
  • Control Hyperlipidemia;
  • Start a walking and exercise program;
  • Surgery;
  • Surgical treatment with bypass of the obstructed area may be the treatment of choice in selected cases.

Medications:

  • Low doses of aspirin may be prescribed. Other medications are: Ticlopidine, Trental;
  • Special medication to increase blood flow may be prescribed, such as calcium channel blockers;
  • Cholesterol lowering medication in patients with elevated cholesterol.

Activity:

  • Daily exercise program. Walking as much as possible (up to 4-5 miles a day), resting if pain or discomfort occurs, and then walk again. Walk on level ground. Keep a log of progress in walking distances;
  • Other daily activities performed as normal.

Prognosis

With surgery, the prognosis is good. Surgery is only possible for large vessels, and may be contra-indicated with other serious illnesses. With medications, disease progression may be slowed. A number of cases do not respond to treatment, and there is usually slow progression to tissue necrosis and gangrene.

Other

Nothing specified.


About

Holly McCain, PharmD is a long-term care pharmacist licensed in multiple states, specializing in skilled nursing, assisted living, ICF/IDD, and medical-at-home services. She has over six years of pharmacy management experience, leading regulatory inspections, supervising multidisciplinary teams, and overseeing sterile IV compounding and pharmacy automation. Her expertise spans Medicare and Medicaid compliance, medication safety, and operational alignment in senior care settings. Holly is an active member of ASCP, AMCP, ASHP, and the Senior Care Pharmacy Coalition.