Search our site RxMed


The comprehensive resource for physicians, drug and illness information
Illnesses information
Pharmaceutical Information
Herbal and dietary supplements
Travel health information
Free registration
About RxMed
Our medical advisory board





GUAIFENESIN
General Monograph
Glyceryl Guaiacolate
Expectorant
Pharmacology: Guaifenesin is believed to produce its effect through a local or reflex irritant action that activates the vagus nerve to stimulate secretion or respiratory tract fluid. This is thought to increase sputum volume, decrease its viscosity, enhance the flow of less viscid secretions and promote mucociliary clearance.

Pharmacokinetics: The drug is rapidly absorbed from the gastrointestinal tract and excreted in the urine.

Indications: An expectorant agent used in the symptomatic relief of respiratory conditions associated with productive cough, with the presence of mucus in the respiratory tract. May also be useful in the management of dry, unproductive cough by easing expectoration of thick, viscous secretions.

Precautions: Consult a physician if cough persists for longer than 7 days or if high fever, skin rash, persistent headache, or sore throat is present with cough.

Guaifenesin may cause a color interference with certain laboratory determinations of 5-hydroxyindoleacetic acid and vanillylmandelic acid.

tag_Adverse Effects:Adverse Effects: Nausea, gastrointestinal upset and drowsiness occur infrequently.

Dosage: Table I provides recommendations on dosing for guaifenesin.