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AMINO-CERV Milex Amino Acids – Sodium Propionate – Urea Cervical Therapy Action And Clinical Pharmacology: Methionine and cystine are amino-acids necessary for wound healing and forming of epithelial tissue. Inositol acts as an essential growth factor and promotes epithelialization. Urea aids in debridement, dissolves the coagulum and promotes epithelialization. Its solvent action on fibroblasts prevents the formation of excessive tissue, thus preventing stenosis when used as directed. Benzalkonium chloride serves…

AMINOHIPPURATE SODIUM MSD Determination of Renal Function Action And Clinical Pharmacology: Aminohippurate Sodium (PAH) is filtered by the glomeruli and is actively secreted by the proximal tubules. At low plasma concentrations (1 to 2 mg/100 mL), an average of 90% of PAH is cleared by the kidneys from the renal blood stream in a single circulation. It is ideally suited for measurement of ERPF since it has a high clearance,…

ALUPENT® Preparations Boehringer Ingelheim Orciprenaline Sulfate Bronchodilator Action And Clinical Pharmacology: Orciprenaline is a bronchodilating agent. The bronchospasm associated with various pulmonary diseases – chronic bronchitis, pulmonary emphysema, bronchial asthma, silicosis, tuberculosis, sarcoidosis and carcinoma of the lung, has been successfully reversed by therapy with orciprenaline. Orciprenaline has the following major characteristics: The action of orciprenaline is one of beta stimulation. Receptor sites in the bronchi and bronchioles are more…

ALLOPURINOL General Monograph, CPhA Xanthine Oxidase Inhibiton This monograph has been compiled by CPhA. It may contain information different from that approved by HPB, Health Canada, and the pharmaceutical manufacturers’ approval has not been requested. Pharmacology: Allopurinol and its active metabolite, oxypurinol, inhibit xanthine oxidase, the enzyme responsible for the conversion of hypoxanthine to xanthine and of xanthine to uric acid. Inhibition of this enzyme accounts for the major pharmacological…

ALIMENTUM® Abbott Infant Feeding Formula Indications And Clinical Uses: A nutritionally complete formula for infants and children with milk and/or soy protein allergy, severe food allergies, colic due to milk sensitivity, select cases of chronic diarrhea or maldigestion/malabsorption. Precautions: Shake very well to assure proper blending. Because of the special nutritional characteristics of Alimentum, it does not look or taste like milk or soy formulations. This is a ready-to-feed formula;…

ALERTONIC® Hoechst Marion Roussel Pipradrol – Vitamin Compound Indications And Clinical Uses: Short-term use in cases of vitamin B deficiencies accompanied by functional fatigue. Contra-Indications: As with other drugs with CNS stimulating action, pipradrol is contraindicated in hyperactive, agitated, or anxious patients and depressive illness, chorea, or obsessive compulsive states. Precautions: Pregnancy: Although animal reproductive studies have not indicated adverse effects, this drug should not be used during the first…

ALBERT® OXYBUTYNIN Albert Pharma Oxybutynin Chloride Anticholinergic – Antispasmodic Agent Action And Clinical Pharmacology: Oxybutynin is a tertiary amine anticholinergic agent which exerts antimuscarinic as well as direct antispasmodic action on smooth muscle. In vitro studies have shown that its anticholinergic effects are weaker than those of atropine, but it possesses greater antispasmodic activity. No blocking effects occur at skeletal neuromuscular junctions or in autonomic ganglia (no antinicotinic effects). In…

ALBERT® GLYBURIDE Albert Pharma Glyburide Oral Hypoglycemic Action And Clinical Pharmacology: The principal action of glyburide results in an increased insulin release from the beta cells of the pancreas. Other mechanisms leading to a reduction of blood glucose are also believed to be influenced by glyburide. The insertion of an alkylene chain on the benzene nucleus results in a product of very high potency. Schulz and Schmidt indicated that the…

AIROMIR™ 3M Pharmaceuticals Salbutamol Sulfate Bronchodilator – b2-adrenergic Stimulant Action And Clinical Pharmacology: Salbutamol produces bronchodilation through stimulation of b2-adrenergic receptors in bronchial smooth muscle, thereby causing relaxation of bronchial muscle fibers. This action results in improved pulmonary function as demonstrated by spirometric measurements. At therapeutic doses, salbutamol has little action on the b1-adrenergic receptors in cardiac muscle. Clinical experience has shown that inhaled salbutamol, like other b-adrenergic agonists, can…

ADVIL® Whitehall-Robins Ibuprofen Analgesic – Antipyretic Indications And Clinical Uses: Adults and Children over 12: For fast and effective relief of headaches, toothache and menstrual pain, and for minor aches and pain associated with arthritis, muscles, joints and backache, and for reduction of fever. Children 12 and under: For fever and pain due to colds, sore throat, immunizatin and earache. Contra-Indications: Hypersensitivity to ibuprofen. Patients with active peptic ulcers or…