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BACTRIM™ ROCHE® Roche Trimethoprim – Sulfamethoxazole Antibacterial Action And Clinical Pharmacology: Trimethoprim plus sulfamethoxazole block 2 consecutive steps in the biosynthesis of nucleic acids and proteins essential to many bacteria. Sulfamethoxazole inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid. Trimethoprim blocks the production of tetrahydrofolic acid from dihydrofolic acid by reversibly inhibiting the required enzyme, dihydrofolate reductase. The effect of the dual consecutive action is to reduce…

BARBITURATES Amobarbital Butabarbital Pentobarbital Phenobarbital Secobarbital Anticonvulsant – Sedative-Hypnotic Pharmacology: Barbiturates are nonselective central nervous system (CNS) depressants, capable of producing all degrees of depression from mild sedation and hypnosis to general anaesthesia, deep coma and death. The extent of CNS depression varies with the route of administration, dose and pharmacokinetic characteristics of the particular barbiturate. Patient specific factors such as age, physical or emotional state and the concomitant use…

BAYCOL® Bayer Cerivastatin Sodium Lipid Metabolism Regulator Action And Clinical Pharmacology: Cerivastatin is an entirely synthetic, enantiomerically pure cholesterol-lowering agent and is structurally similar to the fungal derivatives of this therapeutic class. Cerivastatin is a competitive inhibitor of 3-hydroxy-3methyl-glutaryl-coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the conversion of HMG-CoA to mevalonate, which is an early and rate-limiting step in the biosynthesis of cholesterol. The inhibition of cholesterol biosynthesis by cerivastatin…

BACID® Rh´ne-Poulenc Rorer Lactobacillus acidophilus Flora Modifier Indications And Clinical Uses: To assist in the restoration and maintenance of the normal physiological and bacterial flora of the oral and intestinal tracts. Has been used in the prevention and treatment of postantibiotic stomatitis and microbial diarrheas; also in aphthous and herpetic stomatitis. Precautions: Should be stored in a refrigerator at a temperature of 10°C, or below to maintain potency. Not to…

BACIGUENT® Johnson & Johnson• Merck Bacitracin Topical Antibiotic Indications And Clinical Uses: For the treatment and prevention of infection in minor cuts, wounds and burns. Manufacturers’ Warnings In Clinical States: For external use only. Avoid contact with eyes. If contact occurs, wash thoroughly with water. Use should be discontinued if condition worsens. No refrigeration required. Precautions: Discontinue if sensitization occurs. Prolonged use may result in the overgrowth of nonsusceptible organisms,…

BABY’S OWN™ GRIPE WATER Block Drug Sodium Bicarbonate Compound Antacid – Antiflatulent Indications And Clinical Uses: For fast soothing relief from minor stomach upset, colic, cramps, flatulence and hiccups due to indigestion. Dosage: Shake before using. Newborn infant: 2.5 mL; 1 to 6 months: 5 mL; over 6 months: 10 mL. May be repeated up to 4 times daily as required. If symptoms persist, consult physician. Availability And Storage: Each…

ARTHROTEC® Searle Diclofenac Sodium – Misoprostol Anti-inflammatory – Analgesic – Mucosal Protective Agent Action And Clinical Pharmacology: Arthrotec is a combination of a nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties and a mucosal protective synthetic analog of prostaglandin E1. Arthrotec has been shown to be as effective as diclofenac in reducing the signs and symptoms of rheumatoid arthritis and osteoarthritis. In addition, Arthrotec has been associated with a lower incidence…

AQUATAIN® Whitehall-Robins Emollient Indications And Clinical Uses: Emollient for dry, chapped, rough skin. Dosage: Apply as needed several times daily or as prescribed. Availability And Storage: Cream: Each tube of unscented, hypoallergenic cream contains: benzyl alcohol, polawax, isopropyl palmitate, glycerin, sorbitol, lactic acid and water. Tartrazine-free. Tubes of 75 g. Lotion: Each bottle of unscented, hypoallergenic lotion contains: benzyl alcohol, polawax, isopropyl palmitate, glycerin, sorbitol, lactic acid and water. Tartrazine-free….

AQUASOL® E Novartis Consumer Health Vitamin E Vitamin Action And Clinical Pharmacology: Vitamin E is a fat soluble vitamin which is present in many foods and exists in a variety of forms. It is considered an essential element of human nutrition, with many of its actions related to its antioxidant properties. Indications And Clinical Uses: A nutritional supplement for the treatment of vitamin E deficiency. Vitamin E deficiency states are…

ARALEN® Sanofi Chloroquine Phosphate Antimalarial – Antiparasitic Action And Clinical Pharmacology: Chloroquine has been found to be highly active against the erythrocytic forms of Plasmodium vivax, ovale and malariae and many strains of Plasmodium falciparum (but not the gametocytes of Plasmodium falciparum). The precise mechanism of plasmodicidal action of the drug is not known. While the drug can inhibit certain enzymes, its effect is believed to result, in part, from…