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MICANOL® Canderm Pharma Anthralin Psoriasis Treatment Action And Clinical Pharmacology: Micanol cream provides the action of anthralin in a pharmaceutically elegant base formulated to minimize staining and irritation. With successful treatment, scales will be removed and the lesions will flatten. The lesions will take time to blanch after flattening has occurred. Indications And Clinical Uses: For the treatment of psoriasis. Contra-Indications: Do not use on areas of skin where inflammation…

MAVIK™ Knoll Trandolapril Angiotensin Converting Enzyme Inhibitor Action And Clinical Pharmacology: Trandolapril is a nonsulfydryl angiotensin converting enzyme (ACE) inhibitor, which is used in the treatment of mild to moderate essential hypertension and following acute myocardial infarction in stabilized patients with left ventricular dysfunction. Angiotensin converting enzyme (ACE) is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the pharmacologically active substance, angiotensin II, which is a vasopressor…

MARINOL® Sanofi Dronabinol Antiemetic Action And Clinical Pharmacology: Dronabinol, also known as delta-9-tetrahydrocannabinol has been shown to have psychotropic and antiemetic activity. Dronabinol can produce changes in mood, decrease in cognitive performance and memory, decrease in ability to control drives and impulses, and altered perception of reality, particularly altered time sense. Pharmacokinetics: Dronabinol is readily absorbed from the gastrointestinal tract. The systemic availability, following oral administration, is 10 to 20%…

MACRODANTIN® Procter & Gamble Pharmaceuticals Nitrofurantoin Macrocrystals Urinary Tract Antibacterial Action And Clinical Pharmacology: Nitrofurantoin is reduced by bacterial flavoproteins to reactive intermediates which inactivate or alter bacterial ribosomal proteins and other macromolecules. As a result of such inactivations, the vital biochemical processes of protein synthesis, aerobic energy metabolism, DNA synthesis, RNA synthesis and cell wall synthesis are inhibited. The broad-based nature of this mode of action may explain the…

M-M-R® II MSD Measles, Mumps and Rubella Virus Vaccine, Live, Attenuated, MSD Std Action And Clinical Pharmacology: M-M-R II is for immunization against measles (rubeola), mumps, and rubella (German measles). One injection of M-M-R II consists of Attenuvax (Measles Virus Vaccine, Live, Attenuated, MSD Std), Mumpsvax (Mumps Virus Vaccine, Live, Attenuated, MSD Std) and Meruvax II (Rubella Virus Vaccine, Live, Attenuated, MSD Std). Clinical studies of 279 triple seronegative children,…

M.V.I.-12 (Multivitamin Infusion) Rhône-Poulenc Rorer Multivitamins Vitamin Supplement Indications And Clinical Uses: This formulation is indicated as daily multivitamin maintenance dosage for adults and children aged 11 and above receiving parenteral nutrition. It is also indicated in other situations where administration by the i.v. route is required. Such situations include surgery, (including pre- and post-operative parenteral nutrition), extensive burns, fractures and other trauma, severe infectious diseases and comatose states, which…

MYCOBUTIN® Pharmacia & Upjohn Rifabutin Antibacterial Agent Action And Clinical Pharmacology: Rifabutin is a derivative of rifamycin S, belonging to the class of ansamycins. The rifamycins owe their antimycobacterial efficacy to their ability to penetrate the cell wall and to their ability to complex with and to inhibit DNA-dependent RNA polymerase. Rifabutin has been found to interact with and to penetrate the outer layers of the mycobacterial envelope. Rifabutin inhibits…

MYCOSTATIN® Preparations Squibb Nystatin Antifungal Antibiotic Indications And Clinical Uses: Oral: Prevention and treatment of fun of the oral cavity and esophagus, for intestinal candidiasis and for protection against candidal overgrowth during antimicrobial or corticosteroid therapy. Topical: Treatment of cutaneous or mucocutaneous mycotic infections caused by Candida (Monilia) species. Vaginal: Local treatment of vaginal mycotic infections caused by C. albicans (Monilia) and other Candida species and treatment of pregnant patients…

LIPISORB® Mead Johnson Therapeutic Nutrient Indications And Clinical Uses: A nutritionally complete liquid diet specifically designed for patients with fat malabsorption (e.g., inflammatory bowel disease, cystic fibrosis, short bowel syndrome and HIV infection). It provides complete vitamins and minerals with a readily absorbed fat blend. This vanilla flavored beverage can be fed orally or as a tube feeding. tag_DosageDosage Dosage And Administration: As prescribed by a physician. Tube feeding may…

LIPITOR™ Parke-Davis Atorvastatin Calcium Lipid Metabolism Regulator Action And Clinical Pharmacology: Atorvastatin is a synthetic lipid-lowering agent. It is a selective, competitive inhibitor of 3-hydroxy- 3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, which is an early and rate-limiting step in the biosynthesis of cholesterol. Atorvastatin lowers plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase and cholesterol synthesis in the liver and by increasing…