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Pygeum
contains three groups of active components: Phytosterols such
as beta-sitosterol; pentacyclic triterpenoids, such as ursolic
and oleanic acids; and ferulic esters of fatty acids, particularly
the ferulic esters of docosanol and tetracosanol. The phytosterols,
particucularly beta-sitosterol are found in numerous plants and
are anti-inflammatory, inhibiting the synthesis of prostaglandins.
Beta-sitosterol has been shown to be useful in cases of BPH [
Benign prostatic hyperplasia ] .It does this by reducing the normally
elevated levels of prostaglandins in these patients, and thus
reducing the size of the prostate. This helps to relieve the symptoms
of BPH.
The
pentacyclic triterpenoids also help inhibit inflammation by blocking
enzymatic activity, and reduce swelling of the prostate.
The
ferulic esters of long-chain fatty acids help by inhibiting both
- the absorption and metabolism of cholesterol . Generally, enlarged
prostates are characterized by high levels of cholesterol.
Numerous
double blind clinical trials have demonstrated that pygeum is
effective in treating a wide range of prostatic hyperplasias.
It has been shown that consumption of pygeum extract resulted
in significant amelioration of symptoms of prostatic hyperplasia
, namely dysuria [ painful urination ], nocturia and frequency
as well as reduction in residual urine volume [post -micturition
residue ]. In addition to this ,pygeum also promotes reduction
in the size of the prostate and clearance of bladder neck obstruction
.
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