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| General
Information |
Common Name: |
Green Tea Extract |
|
Latin
Name:
|
Camellia
Sinensis |
|
Family:
|
Theceae |
| Other
Names: |
 |
Tea
|
|
| Indications
& Historical Uses |
|
Green
tea extract is a bioflavonoid-rich potent extract which is a powerful
free-radical antagonist and anti-oxidant. It is used primarily
for its antioxidant & free-radical fighting properties.
Thus
it is used for prevention of atherosclerotic disease, and reducing
blood pressure by its suppression of angiotensin I converting
enzyme.
It
also reduces platelet aggregation, and these properties are applied
in preventing atherosclerosis, and thereby preventing heart disease
and stroke.
It
also combats mental fatigue, and may lower the risk of esophageal,
stomach, colon and skin cancer .
|
| Contraindications
& Precautions |
|
Should
not be used in large quantities during pregnancy and while nursing.
Persons with anxiety disorders, irregular heartbeat should limit
their intake of Green Tea.
Adverse
Side Effects/Drug Interactions:
None known at present. See Caution.
|
| Dosage
Information |
|
Dosage:
|
250
mg to 500 mg of EGCG content daily. |
| Pharmacology
|
|
The
polyphenols in green tea are catechins, with multiple linked ring-like
structures. The dominant polyphenol is EGCG( Epigallocatechin
Gallate), a potent antioxidant, and anti infective.
EGCG
is over 200 times more effective than Vitamin E in neutralizing
pro-oxidants and free radicals that attack brain lipids, in vivo.
EGCG
is suppressive for Angiotension I converting enzyme, which is
a key factor in essential hypertension.
EGCG
also reduces platelet aggregation, inhibits pathogenic bacteria
and finally may be effective in prevention of dental caries by blocking
the attachment of caries-causing bacteria to the teeth and gum tissue. |
|
Active
Ingredients:
|
Catechins,
especially (-) Epigallocatechin Gallate (EGCG) a potent antioxidant
|
| Origin |
|
Semi-tropical
shrub native to China, Japan, South East Asia. About 20%of the
World,s tea market consists of Green Tea.
|
| Processing |
|
Extraction
with hydromethanolic or hydroacetonic solution.
|
| Scientific
References |
|
Chem.
Pharm. Bull., vol. 38,pg. 1049, 1990.
|
|
Tohoku
J. Exp. Med., vol. 166, pg. 475, 1992.
|
|
Carcinogenesis,
vol. 13, pp. 947 & 1491, 1992.
|
|
Cancer
Res., vol. 52, pp. 1162, 1943, 3875, 4050, 6657 & 6890,
1992.
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Cancer
Lett., vol. 65, pg. 51, 1992.
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Muramatsu,
K., Fukuyo, M., & Hara, Y., Effect of green Tea Catechin
on Plasma Cholesterol Level in Cholesterol-Fed Rats, J.
Nutr.Sci. Vitaminol., vol. 32, pp. 613-622, 1986.
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Sagasaka-Mitane, Y., Miwa, M., & Okada, S., Platelet Aggregation
Inhibitors in Hot Water Extract of Green Tea, Chem. Pharm.
Bull., vol.38(3), pp. 789-793, 1990.
|
|
Horiba,
N., et al., A Pilot Study of Japanese Green Tea as a Medicament:
Antibacterial and Bactericidal Effects, Journal of Endodontic,
vol, 17 (3), pp. 122-124, 1991.
|
|
Hattori,
M., et al., Chem. Pharm. Bull., vol. 38, pg. 717,
1990.
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| Back
To Index |
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